Advarra

Advarra is a comprehensive clinical research platform company that provides the technology, insights, and operational expertise needed to make clinical trials more efficient and connected. Built on more than 40 years of IRB leadership—rooted in the legacy of Schulman IRB and Chesapeake IRB—Advarra serves the entire research ecosystem, connecting sponsors, CROs, and research sites across the full trial lifecycle. The company combines its industry-leading IRB oversight with an integrated suite of clinical trial management, data, and AI-powered solutions to help study teams streamline operations, reduce burden, and accelerate the path to bringing new therapies to patients.

Advarra's scale and reach reflect its position as a trusted partner across the industry. More than 50,000 investigators utilize Advarra trial technology solutions, over 12,000 open protocols are overseen by Advarra annually, 88% of NCI-designated cancer centers use Advarra technology, and 3,500+ institutions, hospitals, health systems, and academic medical centers rely on the company. All of the top 10 pharmaceutical sponsors and CROs use Advarra IRB.

IRB Oversight

• Advarra IRB provides independent, rigorous ethical oversight with the speed, expertise, and transparency that modern research demands.
• Backed by decades of IRB leadership, the IRB team is dedicated to ensuring research progresses with confidence, efficiency, and care.
• Strict firewalls between IRB and commercial operations preserve objectivity and uphold the integrity of every study.
• IRB oversight serves the trial as a whole—not any single stakeholder—ensuring research advances ethically, credibly, and efficiently.

Braid — Data and AI Platform

• Braid is Advarra's data and AI platform, designed to weave operational intelligence into every stage of the trial lifecycle.
• Powered by operational data from Advarra's IRB and clinical trial systems, Braid delivers actionable insights for smarter study design, faster decisions, and AI-automated workflows.
• Advarra recently launched a Study Design Solution powered by Braid, aimed at improving operational efficiency in clinical trials through AI-powered protocol optimization.

Solutions for Sites and Institutions

• CTMS: OnCore and Clinical Conductor provide enterprise-wide clinical trial management system capabilities for research sites and institutions.
• eReg: Efficient regulatory document management and exchange to support compliance workflows.
• eSource: Integrated data capture and oversight tools for streamlined site operations.
• Strategic Enablement: Optimization services covering operations, compliance, technology, billing, and finance to help sites maximize performance.

Solutions for Sponsors and CROs

• Study Design: AI-powered protocol optimization to improve study design decisions from the outset.
• Site ID and Feasibility: Site performance insights and automated qualification to identify the best sites for each study.
• Study Startup: Shared and transparent guided activation workflows to accelerate site initiation.
• Site Collaboration and Training: Integrated document exchange and AI-powered training tools to align sites and sponsors.
• Enrollment Planning and Tracking: Streamlined patient referrals and real-time recruitment visibility to support enrollment goals.

Connected Ecosystem and Integrations

• Integrations between Advarra applications provide shared visibility into study startup progress, IRB status, and continuous study monitoring.
• Patient referrals and essential documents flow between systems with ease, reducing manual effort and improving data quality.
• Secure, automated data flow between EHR, EDC, and eSource systems reduces staff burden and accelerates the pace of discovery.
• The platform enables sponsors, CROs, and sites to work as one connected ecosystem by removing barriers and streamlining workflows.

Company Values and Principles

• Progress with purpose: Every innovation is intentional, validated, ethical, and designed to deliver meaningful value to customers and trial participants.
• Deep expertise: With 40+ years of IRB leadership, decades of site and sponsor enablement, and the industry's largest trial operations dataset, Advarra guides customers through the most complex parts of the trial lifecycle.
• Objectivity: Independence is maintained through strict firewalls, ensuring the integrity of every study.
• Collaboration: Advarra champions a connected research community, bringing sponsors, sites, and CROs together to create transparency and alignment.

Diversity, Equity, and Inclusion

• Advarra fosters a work environment where employees feel comfortable bringing their authentic selves to work, valuing diversity across race, ethnicity, religion, gender identity, sexual orientation, national origin, age, veteran status, and disability.
• The company actively seeks ways to assist clients in increasing participation of underrepresented populations in clinical trials through its products and services.
• Advarra regularly partners with industry thought leaders to address DE&I challenges within clinical research.

Global Presence

• Headquartered in Columbia, Maryland, with additional offices in Wellesley, Massachusetts; Aurora, Ontario, Canada; Bangalore, India; Limerick, Ireland; and remote teams spanning research hubs worldwide.
• Advarra combines global reach with local expertise to support partnerships across the international research community.

Trusted by the world's leading pharmaceutical sponsors, CROs, academic medical centers, and research sites, Advarra continues to evolve as a comprehensive partner to the entire clinical research ecosystem—pairing its foundational IRB integrity with advanced technology and intelligence to help study teams pursue clinical advancement with confidence, efficiency, and care.