Site Collaboration & Training

Advarra's Site Collaboration & Training is a clinical trial operations platform designed for sponsors and CROs seeking to work more efficiently with investigative sites. By combining secure document exchange, AI-powered study training, and centralized single sign-on (SSO) access, the solution streamlines study startup, accelerates site readiness to enroll, and maintains continuous audit readiness throughout the trial lifecycle.

The platform is purpose-built to support site-centric workflows while ensuring sponsors and CROs retain centralized visibility, compliance oversight, and seamless integration with core source systems such as eTMFs and site-owned eISF/eReg systems.

Secure Document Exchange

• Accelerate study startup through end-to-end integration and automated, seamless exchange of research documents between sites, sponsors, CROs, and Advarra's IRB.
• Centralize all document management in a single, connected environment.
• Integrate directly with site-owned eISF and eReg systems to support site-centric workflows.
• Enhance regulatory compliance and guarantee version control across all documents.
• Enable "always-on" audit readiness so teams are perpetually inspection-ready.

Study Training Capabilities

• Deliver study-specific, engaging training content to replace or supplement traditional in-person investigator meetings, increasing protocol comprehension.
• Enable site staff to securely chat with study documents using AI-powered functionality.
• Deploy task-based and event-based training to ensure the right training reaches the right staff at the right time.
• Manage assessment and certification workflows to confirm site staff competency.
• Expedite sites' readiness to enroll by reducing time spent on non-study-specific training — one customer, AMR Clinical, reduced training time from approximately two weeks down to three to six hours.
• Ensure protocol compliance and reduce redundant training burdens on sites.
• Oversee and store training records with real-time, actionable visibility into site compliance for sponsor and CRO teams.
• Quickly deploy and train site staff on protocol amendments as they arise.

Centralized SSO and Study Application Access

• Eliminate additional logins by enabling both sites and study teams to access all essential study systems using their own organization credentials.
• Deploy a study's "digital front door" to centralize access to all study applications.
• Reduce critical time spent on technology setup and access management at study startup.
• Bolster security and ensure compliance through standardized authentication.
• Improve audit trails, maintain staff directories, and manage access continuity through staff turnover.

Integration with Sponsor and Site Core Source Systems

• Support site-centric workflows while automatically routing all documents centrally to the sponsor's eTMF for long-term storage and always-on inspection readiness.
• Route documents for site signature within the Study Collaboration solution; once signed, automatically send a read-only, compliant copy to the site's Advarra eReg inbox.
• Provide a sponsor-supplied document management system for sites that do not have their own eISF, enabling them to manage study documents within the platform.
• Automate the flow of all mandatory regulatory and IRB documents into the eTMF to eliminate manual document chasing and ensure complete trial master file integrity.

Advarra's Site Collaboration & Training integrates with sponsors', CROs', and sites' existing technology ecosystems, including eISF, eReg, and eTMF systems. The platform supports compliance, security, and audit readiness requirements throughout the clinical trial, and has demonstrated measurable outcomes including doubled recruitment rates and reduced screen failures across large, multi-site studies.