Patient Feasibility

Patient Feasibility is a module within TrialHub designed to help pharmaceutical companies, CROs, and biotechs conduct patient feasibility assessments before and during clinical trial design. It provides real-time insights into patient pathways, standard of care (SoC), unmet needs, and treatment access on a country-by-country basis, with the goal of reducing protocol amendments, recruitment delays, and associated costs.

The tool is built around the premise that understanding the local patient journey — from diagnosis through treatment — is essential for designing protocols that work in practice. Users reported outcomes including 20x fewer hours spent on standard of care research, 3x faster recruitment, and $1.6M saved on major amendments in a single quarter. Boehringer Ingelheim noted that TrialHub reduced analysis time from 3–6 months to several hours.

Core Capabilities

• Identifies where eligible patients are located across countries being considered for trial sites.
• Provides insight into patients' disease burden and unmet healthcare needs.
• Maps patient treatment pathways and local standard of care practices.
• Estimates the potential number of patients who need a given treatment in each country.
• Checks reimbursement status of comparator drugs and existing treatments by country.
• Assesses whether local SoC would render patients ineligible for a trial, flagging potential recruitment challenges before they arise.
• Supports control arm design by benchmarking against existing reimbursed treatments.

Protocol Development and Validation

• Supports design of trial protocols that align with local treatment practices rather than theoretical standards.
• Enables comparison of an investigational therapy against regional treatment standards to assess whether it addresses genuine unmet needs.
• Provides data to predict commercial viability and potential market impact of a therapy.
• Informs product development strategy with country-level data on treatment access and patient availability.

Understanding the Patient Journey

• Provides a country-by-country view of the patient journey from diagnosis to treatment.
• Helps answer where a trial fits within the patient journey and at what stage patients become eligible.
• Identifies unmet needs that a trial can address.
• Highlights factors that affect patient retention and ease of participation.
• Includes interface views such as Nested View, Alignment View, Notebook, and Notifications to support different analytical workflows.

Use Cases by Organisation Type

• Pharma: Reducing costs from avoidable amendments, predicting recruitment challenges, and developing real-world protocols.
• CRO: Accelerating proposal creation, designing sponsor-ready trial strategies, and monitoring the evolving SoC landscape to prevent recruitment delays.
• Biotech: Validating product-market fit, selecting appropriate study strategies, and monitoring the clinical landscape to manage risk.

Support and Service Model

• Includes an "Ask the Analyst" feature that provides access to a dedicated team of medical experts, analysts, and data scientists.
• Support team proactively monitors user searches and refines parameters when results do not meet expectations.
• Product roadmap is developed in response to user needs.

TrialHub's Patient Feasibility module is used by organisations including Avance Clinical, Premier Research, Advanced Clinical, Boehringer Ingelheim, Bionical Emas, and AICROS. The platform is available via demo request and is positioned for use across the full spectrum of clinical trial planning, from early feasibility through site and country selection.