MassHunter Software

MassHunter is Agilent's comprehensive mass spectrometry application software suite designed to support the full analytical workflow for GC/MS and LC/MS systems. It covers data acquisition, qualitative and quantitative data analysis, mass spectral library management, and simplified user interfaces — making the power of mass spectrometry accessible to users at all experience levels across a wide range of industries and applications.

The MassHunter software suite is suited for laboratories in biopharma, environmental testing, food and beverage, clinical research, omics, and many other fields. By combining straightforward instrument control with powerful analytical tools and application-specific software, MassHunter enables efficient, reliable sample analysis from acquisition through reporting.

Data Acquisition

• Provides straightforward setup and operation of the entire LC/MS or GC/MS system
• Supports both GC/MS and LC/MS instrument platforms within a unified acquisition environment
• Simplifies system configuration to reduce the complexity of getting started with mass spectrometry analysis

Data Analysis

• Offers a broad suite of powerful data analysis tools designed to streamline the analytical workflow for any sample task
• Includes qualitative analysis software for in-depth MS data interpretation
• Provides quantitative analysis software for accurate and reproducible MS quantitation
• Features AI Peak Integration Software for MassHunter Quant, which replaces manual peak integration with adaptable, AI-assisted peak detection and integration — particularly beneficial for analytical test labs using single quadrupole GC/MS
• Includes MassHunter BioConfirm software for biopharmaceutical characterization, with version 12.0 and 12.1 offering enhanced capabilities for peptide and protein analysis
• Nine data analysis products are available within the suite, covering a wide range of application-specific needs

Library Management

• ChemVista is a flexible mass spectral library manager designed for Q-TOF/MS instruments
• Comes with extensive preloaded, curated libraries and databases to facilitate the identification of unknown compounds
• Supports unknowns identification workflows, enabling researchers to confidently characterize complex samples
• Three library management products are available within the MassHunter suite

Simplified Interfaces

• Provides simplified software interfaces that give any user — regardless of mass spectrometry expertise — access to the full power of MS instrumentation
• Tailored, application-specific software tools reduce the learning curve and enable more efficient operation
• Designed to democratize access to mass spectrometry across laboratory environments

Recent Innovations and Updates

• AI Peak Integration Software introduced at ASMS 2023 brings intelligent, automated peak detection and integration to replace time-consuming manual processes
• MassHunter BioConfirm 12.1 Software released with enhanced biopharmaceutical analysis capabilities
• The Agilent ExD Cell, available for the 6545XT AdvanceBio LC/Q-TOF, adds electron capture dissociation (ECD) to enhance peptide and protein characterization, complementing MassHunter software workflows
• The Agilent 7010D Triple Quadrupole GC/MS System features the new HES 2.0 ion source with attogram-level sensitivity, supported by MassHunter data acquisition and analysis software

MassHunter software is tightly integrated with Agilent's GC/MS and LC/MS instrument platforms and is supported by a broad range of educational resources, including FAQs, community forums, webinars, and training through Agilent University. Compliance and software qualification services are also available to support regulated laboratory environments.