GLIMS HLA Transplant Module

The Clinisys GLIMS HLA Transplant Module is a specialised laboratory information system (LIS) module designed to organise and automate all immunogenetic and HLA processes. It is built for transplant laboratories and clinical teams who need to manage HLA typing, track antibody test results, and optimise graft compatibility in order to improve patient outcomes. With an intuitive user interface and advanced functionality, the module helps laboratories save time, reduce errors, and access well-organised information to support confident clinical decision-making.

The module integrates seamlessly with national and international databases such as the Eurotransplant network, enabling real-time updates and ensuring maximum data security. It is part of the broader Clinisys GLIMS ecosystem and supports laboratories in delivering high-quality, traceable, and efficient transplant care.

Core HLA Workflow Management

• Manages HLA typing and longitudinal tracking of antibody test results
• Delivers the right information at the right time to support graft compatibility optimisation
• Automates and streamlines HLA workflows according to the clinical context of the recipient or donor
• Eliminates duplicate tests and unnecessary repetitions
• Provides immediate visibility into the latest status of requested HLA tests
• Simplifies laboratory administration while increasing accuracy and efficiency

Longitudinal MFI Value Tracking

• Ensures high accuracy in tracking Mean Fluorescence Intensity (MFI) values for reliable results
• Maintains strict data traceability so that every measurement is precise and reproducible
• Integrates MFI tracking into laboratory workflows, giving technicians easy access to both historical and current data
• Enables rapid detection of abnormal fluctuations over time, supporting more accurate diagnosis and clinical decision-making
• Provides clinicians with an overview of MFI trends so that treatment can be adjusted to optimise patient care

Virtual Crossmatch Management

• Manages the virtual crossmatch process, which is essential for rapid assessment of immunological compatibility between recipient and donor
• Helps reduce cold ischaemia time by removing the need to wait for actual crossmatch results, thereby accelerating the transplantation process and preserving graft viability
• Enables better planning and utilisation of operating theatres by optimising scheduling and reducing waiting times
• Can be performed remotely, facilitating coordination between teams handling samples from different regions
• Incorporates standards established by associations such as the European Federation of Immunogenetics (EFI), ensuring secure and compliant data management

Integration with National and International Databases

• Features a dedicated interface to manage HLA status and results from national and international databases, including Eurotransplant
• Supports daily monitoring of graft status through connected donor management databases
• Provides access to comprehensive, high-quality information that is critical for epidemiological studies and clinical research
• Contributes to improved quality of medical analyses and decisions

Automation and Technical Workflow Traceability

• Connects with pre-analytical and analytical instruments to integrate results in a structured manner
• Provides a clear overview and organised presentation of patient information and medical history
• Reduces the time required for repetitive and complex tasks, freeing laboratory staff to focus on higher-value activities
• Ensures full traceability of all technical processes within the laboratory

JSON Data Format for Flexible Data Management

• Uses JSON as its data format, enabling laboratories to manage their data more autonomously
• JSON is easy to read and write, simplifying data management and reducing the risk of errors
• Compatible with many programming languages, facilitating integration with various systems and tools used in the laboratory
• Supports representation of complex data as key-value pairs, allowing information to be structured logically and consistently
• Ensures better compatibility with other systems and technologies

The Clinisys GLIMS HLA Transplant Module is designed to integrate within the wider GLIMS laboratory information system platform, which is cloud-capable and suited to heterogeneous laboratory environments. Compliance with EFI standards is built into the virtual crossmatch functionality, supporting safe and regulated transplant workflows across regional and international settings.