SOPHiA GENETICS

SOPHiA GENETICS is a data-driven medicine company dedicated to democratizing access to advanced analytics for clinicians treating patients with cancer and rare disorders. By combining artificial intelligence with multi-modal biological and medical data, the company helps healthcare providers generate real-time, actionable insights that improve patient outcomes across oncology and rare disease disciplines.

The company serves a broad range of stakeholders, including oncologists, radiologists, pathologists, geneticists, lab technicians, and bioinformaticians, as well as BioPharma organizations seeking diagnostic and data analytics capabilities. SOPHiA GENETICS also engages directly with patients and supports the broader life sciences community through open innovation and industry collaborations.

SOPHiA DDM™ Platform Overview

• The SOPHiA DDM™ (Data-Driven Medicine) platform is the company's core offering, designed to unlock insights and transform healthcare delivery.
• The platform spans genomics, radiomics, and multimodal data analysis, enabling institutions to derive novel biological and clinical insights from diverse data types.
• Professional Services are available to help organizations accelerate breakthroughs through tailored enablement and implementation support.

SOPHiA DDM™ for Genomics

• Oncology applications cover solid tumors, blood cancers, hereditary cancers, and liquid biopsy, supporting comprehensive genomic profiling across cancer types.
• Rare and Inherited Disorders modules address both rare disorders and inherited disorders, enabling genetic analysis for complex and underdiagnosed conditions.
• Alamut™ Visual Plus is an add-on module providing advanced variant interpretation capabilities to support clinical decision-making.
• OncoPortal™ Plus is an additional module designed to enhance oncology reporting and data management workflows.

SOPHiA DDM™ for Radiomics

• This module unlocks entirely novel insights from radiology images, extending the platform's analytical capabilities beyond genomic data into imaging-based diagnostics.

SOPHiA DDM™ for Multimodal

• Deep Lung IV is a multimodal application that explores new frontiers in lung disease biology through integrated data analysis.
• UroCCR is a multimodal solution focused on urological cancers, combining multiple data modalities to generate deeper clinical insights.

BioPharma Solutions

• SOPHiA GENETICS supports BioPharma customers across the full value chain, including diagnostics development, data analytics, and deployment of data-driven solutions.
• Capabilities span drug discovery, clinical development, and commercial deployment phases, enabling pharmaceutical and biotech companies to leverage real-world genomic and clinical data.

Technology and Innovation

• The company's technology is grounded in defined scientific principles and a commitment to open innovation.
• SOPHiA GENETICS actively pursues industry collaborations and maintains a strong publication record, reflecting its engagement with the broader scientific community.

Through its SOPHiA DDM™ platform and a growing ecosystem of genomic, radiomic, and multimodal tools, SOPHiA GENETICS continues to advance its mission of making data-driven medicine accessible to clinicians and researchers worldwide.