MetaSense

MetaSense is a comprehensive software solution designed to streamline metabolite identification (MetID) processes. It consolidates prediction, data analysis, and visualization into a single interface, allowing users to make informed, data-driven decisions efficiently. By integrating all MetID data, users can view and analyze their data in one place, eliminating the need to switch between multiple programs.

The software features auto-generated biotransformation maps and kinetic plots, enabling users to interactively explore their data at various depths. Users can reprocess data directly within MetaSense and draw conclusions about a drug candidate’s metabolism and viability.

Key Benefits

• Comprehensive Analysis: View chromatograms, spectra, biotransformation maps, metabolite tables, and kinetic plots all at once.
• Interactive Data Review: Access raw data easily through interactive links, allowing for direct reanalysis from summary tables or plots.
• Efficient Reporting: Generate customizable reports to share results across your organization.

MetaSense supports a wide range of features, including a built-in probabilistic model for predicting metabolites, the ability to define unique metabolic reactions, and the option to filter metabolites based on specific Phase I & II reactions. Users can import prediction lists from third-party software or manually add missing metabolites as needed.

The software supports batch processing of data and handles all data from related incubation studies simultaneously. It includes a fractional mass filter for detecting unexpected metabolites and verifies structures using MS/MS spectra and logD predictions.

MetaSense is designed to be vendor-agnostic, supporting over 150 file types and thousands of instruments, making it compatible with any LC and MS instruments. It can be integrated into corporate IT environments for automated data import, enhancing workflow efficiency.

Built on JavaScript, MetaSense is accessible from any browser and allows for the creation of detailed reports in various formats. It also provides a web portal for collaborators to access data and results, facilitating seamless data sharing and collaboration.