ZTRON Lite & Pro

ZTRON Pro and ZTRON Lite are on-premises NGS bioinformatics server systems from Complete Genomics, designed to maximize actionable information from DNBSEQ high-throughput sequencers. These systems deliver fast, locally-controlled data analysis by integrating LIMS functionality, bioinformatics accelerators, and high-performance data storage into a unified platform suited for laboratories and traditional data centers.

The two tiers address different scales of bioinformatics need: ZTRON Lite provides a streamlined, automated solution for primary analysis and FASTQ file generation, while ZTRON Pro offers a comprehensive, high-performance environment supporting both primary and secondary analysis, large-scale genomic storage, and advanced compute capabilities including WGS/WES workflows.

ZTRON Lite Key Capabilities

• Automatic and seamless generation of FASTQ files from raw sequencer output
• Fast optical fiber connection enables the DNBSEQ-T7 to upload raw data (.cal files) to ZTRON Lite simultaneously during sequencing
• Automatic conversion of raw data to FASTQ files without manual intervention
• 30TB SSD storage capacity
• 40 CPU cores and 192GB total RAM
• Includes ZLIMS Lite laboratory information management system
• Supports primary analysis workflows

ZTRON Pro Key Capabilities

• Integrates a full laboratory information management system (ZLIMS Pro), bioinformatics accelerator, and high-performance genetic data storage
• Supports both primary and secondary analysis workflows
• High-performance computing clusters with embedded GPU and FPGA accelerators for speedy results and reduced IT maintenance costs
• Available in 500TB or 1PB storage configurations with aggregated storage throughput up to 7GB/s
• 256 CPU cores and 1TB total RAM for demanding computational workloads
• Supports HDD and SSD hard disk types
• Multi-node architecture for scalable deployments
• Supports WGS and WES analysis pipelines
• Additional applications available beyond core analysis workflows
• Designed for both laboratory and traditional data center environments

ZTRON Pro vs. ZTRON Lite: Feature Comparison

• Primary Analysis: Supported on both ZTRON Pro and ZTRON Lite
• Secondary Analysis: Available on ZTRON Pro only
• Storage Capacity: 1PB (ZTRON Pro) vs. 30TB (ZTRON Lite)
• CPU Cores: 256 (ZTRON Pro) vs. 40 (ZTRON Lite)
• Total RAM: 1TB (ZTRON Pro) vs. 192GB (ZTRON Lite)
• FPGA Acceleration: Included in ZTRON Pro; not available in ZTRON Lite
• Multiple Node Support: Available in ZTRON Pro only
• WGS/WES Workflows: Supported in ZTRON Pro only
• Additional Applications: Available in ZTRON Pro only

End-to-End Workflow Integration

• ZTRON systems are part of a complete genomics workflow ecosystem that includes kits and reagents, lab automation, sequencing platforms, and software and analysis tools
• Compatible with conversion kits for third-party library preparation
• Proprietary algorithms are built into each sequencer for secure, fast, and accurate sequencing reads
• Solutions span from sample extraction through lab automation to final data analysis

ZTRON Pro is compliant with GDPR regulations, making it suitable for organizations with strict data privacy requirements. Both systems are offered by Complete Genomics, headquartered in San Jose, California, and are designed to work seamlessly with DNBSEQ sequencing platforms supporting applications including PCR-free WGS, haplotype-phased WGS, spatial omics, and more.