TrialPro

TrialPro is a clinical trial budgeting and coverage analysis platform developed by UpSite Clinical. It is designed for clinical research sites, sponsors, and contract research organizations (CROs), providing a shared environment where all parties can align on budget assumptions, conduct Medicare coverage analysis, and reduce the time required to activate a study. The platform applies AI to automate tasks that have traditionally required weeks of manual effort.

UpSite Clinical states that TrialPro does not send protocol or pricing information to any public AI models, which is relevant for organizations with data privacy requirements around sensitive trial documentation.

Core Platform Capabilities

• Automated clinical trial budgeting that reduces manual effort in building and reviewing budget line items
• AI-powered Medicare coverage analysis to determine which trial activities qualify for standard-of-care billing versus research billing
• Fair market value benchmarking built on defensible data that both sites and sponsors can reference during negotiations
• Shared budget environment that allows sites, sponsors, and CROs to work from aligned assumptions, reducing back-and-forth revisions
• Clear rationale and methodology attached to each budget line item to support defensible, explainable budgets

Workflows by User Type

• For Sites: Build complete study budgets faster, identify work items that might otherwise be missed, and apply benchmarks relevant to the specific site context
• For Sponsors and CROs: Design consistent budgets across studies using precise benchmarks, improve total study cost estimates, and align with sites earlier in the startup process

Study Startup Benefits

• Reduces time from protocol receipt to study activation
• Targets a reduction of study startup time by approximately half through AI-assisted budgeting and coverage analysis
• Decreases rework across teams by establishing shared assumptions early in the process
• Addresses budget misalignment, which is identified as a primary source of delays in study startup

TrialPro is positioned as a platform serving the full clinical trial ecosystem — sites, sponsors, and CROs — within a single shared budgeting environment. UpSite Clinical maintains strategic relationships with leading clinical research organizations and offers demo access for organizations evaluating the platform.