Strand NGS

Strand NGS (formerly Avadis NGS), developed by Strand Life Sciences, is an integrated platform for the analysis, management, and visualization of next-generation sequencing (NGS) data. It is intended for research use and supports a broad range of NGS experiment types, making it applicable to genomics researchers working across multiple sequencing modalities.

The platform provides end-to-end workflows covering alignment through biological interpretation, with dedicated modules for RNA-Seq, DNA-Seq, ChIP-Seq, small RNA-Seq, Methyl-Seq, and MeDIP-Seq experiments. A server edition is also available for multi-member teams.

Alignment and Data Quality Control

• Identifies and filters reads with poor mapping and alignment qualities
• Provides visualizations for mapping quality, coverage, and other alignment metrics

RNA-Seq Analysis

• Supports differential gene expression analysis
• Identifies novel genes, exons, and novel splice junctions

DNA-Seq Analysis

• Detects sequence variants and identifies their effect on transcripts
• Identifies structural variants and copy number variations (CNVs)

ChIP-Seq Analysis

• Identifies transcription factor binding sites and histone modification sites
• Supports peak calling using the PICS and MACS algorithms

Small RNA-Seq Analysis

• Detects differentially expressed small RNAs
• Identifies novel small RNA genes
• Supports identification of mRNA targets

Methyl-Seq and MeDIP-Seq Analysis

• Detects differentially methylated regions and cytosines
• Supports study of methylation effects

Visualization Capabilities

• Provides rich visualizations including poor quality read identification, mapping quality views, variant support views, and coverage plots
• Includes an integrated genome browser for visualizing annotations and multiple genomic regions at different zoom levels

Biological Interpretation

• Supports analysis of gene interactions using information from literature and canonical pathways
• Includes pathway analysis as part of downstream interpretation workflows

Server Edition

• Designed to support multi-member teams working collaboratively on NGS data analysis
• A virtual edition of Strand NGS is also available

Strand NGS is designated for research use only and is not intended for use in diagnostic procedures in the US. The platform offers a 20-day free trial, and learning resources including webinar recordings, demo tutorials, video tutorials, manuals, white papers, and a scripts library are available to support users.