Protein Metrics

Protein Metrics by Dotmatics is a comprehensive proteomics and biotherapeutic analysis platform designed to accelerate mass spectrometry data analysis and reporting. Trusted by over 200 biopharmaceutical companies and 300 academic institutions, it enables researchers to move from discovery-stage protein characterization through to regulated production environments within a single, unified platform.

Whether identifying proteins for proteomics workflows or determining biotherapeutic heterogeneity, Protein Metrics provides substantially more information than previous technologies, eliminating the need for time-consuming manual analysis by experts. The platform is built to serve both discovery and quality-focused teams, supporting Critical Quality Attribute confirmation alongside deep biological insight generation.

Core Platform Capabilities

• Accelerated Biotherapeutic Reporting: Vendor-neutral, templated, and configurable workflows allow data from any instrument or vendor to be analyzed on one platform, ensuring reproducibility and consistent cross-experiment comparison.
• Deeper Insights: Manage, interrogate, and share files and reports generated from any analytical lab. Easily find past experiments, reuse knowledge, and uncover fresh insights using metadata, deep query functionality, and interactive dashboards.
• Compliance-Ready Validation: Seamlessly transition from non-GxP to GxP environments within the same platform. Signature workflows and a full audit trail enable system suitability monitoring, with alerts to confirm the robustness of results and eliminate erroneous findings.

Key Features and Benefits

• Scalable Capacity: Dynamically scales to handle large volumes of data and computational load, ensuring researchers are never limited by infrastructure constraints with on-demand capacity.
• Automated Processing: Files are transferred and processed unattended, saving time and eliminating inconsistencies — particularly valuable for routine workflows.
• Mutualised Knowledge: Expert know-how is captured and embedded within workflows, allowing expertise to be faithfully disseminated across teams and freeing researchers to focus on higher-level challenges.
• Single Platform from Discovery to Regulated: The same environment is used in both regulated and non-regulated settings, simplifying method hand-off between departments and reducing the complexity of validation processes.
• Vendor Neutral, Open Platform: Analytically neutral across vendor data formats and agnostic to IT infrastructure for deployment, enabling plug-and-play integration regardless of raw data source or informatics architecture.
• Cross-Project Dashboards: Combines processed data and metadata to provide facile views across the full range of raw, processed, and internal data. Views and data are dynamic and interrogable, offering a broader contextual landscape of features across experiments.

Workflow and Reporting

• Configurable, templated workflows support both discovery-stage deep characterization and production-stage quality confirmation.
• Customized reporting templates can be created and shared across users, ensuring consistent documentation standards throughout the organization.
• The platform integrates a search engine, data evaluation tools, and a powerful documentation and reporting suite within a single solution, as highlighted by users at Roche.
• Dynamic dashboards allow scientists to interrogate data in context, moving beyond static views to explore the full range of experimental findings interactively.

Protein Metrics by Dotmatics supports flexible deployment and is designed to integrate with existing IT infrastructure and analytical instrument ecosystems. Its compliance-ready architecture makes it suitable for organizations operating under GxP requirements, while its open, vendor-neutral design ensures broad compatibility across biopharmaceutical and academic research environments.