POP

The GenomOncology Precision Oncology Platform (POP) is a modular, scalable infrastructure designed to power precision oncology programs at healthcare institutions of all sizes. Built to grow alongside an institution's evolving needs, POP provides a unified foundation from which organizations can deploy targeted solutions today and seamlessly expand capabilities over time. Trusted by 50+ leading healthcare institutions, GenomOncology transforms complex oncology data into actionable, strategic insights that improve patient care.

POP supports three core solution areas — Molecular Pathology, Clinical Trial Optimization, and Data Enablement — each built on the same secure, integrated platform. GO Connect and a comprehensive API suite enable bidirectional data flow with virtually any institutional system, ensuring GenomOncology enhances rather than disrupts existing workflows.

Core Platform Capabilities

• Secure & Scalable Infrastructure: Cloud-ready or on-premise deployment with enterprise-grade security and HIPAA compliance
• Data Enablement: Automated extraction, normalization, and enrichment of oncology data from any source
• Knowledge & Analytics: Curated, continuously updated oncology knowledge base with advanced visualization tools
• Artificial Intelligence: Transparent, explainable AI delivering decision support across the care continuum

Solutions Offered

• Molecular Pathology: Streamlines NGS workflows from data ingestion through to compliant report delivery
• Clinical Trial Optimization: Accelerates enrollment, expands patient access, and ensures no trial opportunity is missed
• Data Enablement: Transforms unstructured data into strategic assets for registries, analytics, and AI/ML applications

Content & Annotations Knowledge Base

• FDA-Approved Therapies: Comprehensive database of FDA-approved oncology drugs, biomarker-therapy associations, approval dates and indications, resistance mechanisms, and updates delivered within 24 hours of FDA announcements
• Clinical Trials Database: 15,000+ active oncology trials with structured eligibility criteria, contact information and site locations, automated updates from ClinicalTrials.gov, and support for custom institution trial curation
• Annotation Sets: HGVS variant nomenclature, gnomAD population frequencies, ClinVar pathogenicity classifications, OncoKB, CIViC, and other precision oncology databases, plus PubMed literature references

Deployment Options

• Cloud Deployment: Rapid deployment in as little as 3 weeks, managed infrastructure and updates, elastic scalability, reduced IT burden, and support for AWS, Azure, or Google hosting with containerized Docker deployment
• On-Premise Deployment: Full data sovereignty, integration with existing infrastructure, custom security configurations, air-gapped options available, and containerized Docker deployment

GenomOncology's fully containerized architecture provides unmatched deployment flexibility, adapting to cloud, on-premise, or hybrid institutional requirements. With HIPAA-compliant infrastructure, deep integration capabilities, and a continuously curated oncology knowledge base, POP is built to make precision medicine scalable, seamless, and accessible for every patient.