MultiQuant

MultiQuant software is a mass spectrometry quantification tool developed by SCIEX for processing and quantifying large batches of data from both large and small molecule analyses. It is compatible with all SCIEX QTRAP, triple quadrupole, and TripleTOF LC/MS/MS systems and is designed for use in both regulated and non-regulated laboratory environments. The software targets analysts across a range of fields and experience levels, with a focus on reducing data processing time and improving throughput.

The software processes MRM, UV, ADC, and full scan data for quantitation, making it applicable to a broad range of workflows including protein and peptide quantitation, forensic panels, food contaminant analysis, and bioanalytical assays with hundreds or thousands of analytes.

User Interface and Data Review

• Organized interface designed to minimize mouse clicks and reduce the data review bottleneck when extracting quantitative information from sample sets.
• Flexible display tools allow users to fine-tune the interface based on specific data processing needs.
• Linked panes automatically display chromatographic peaks and integration results when a sample is selected.
• Single-click access to view all analytes or a specific analyte, with automatic updates to results tables and peak review.
• Ability to sort MRM data by quality or signal-to-noise ratio, enabling reviewers to focus on the lowest-scoring MRM transitions.
• Overlay view of multiple MRM transitions for the same species to assess peak shape and scan for possible peak interferences in selected channels.
• Supports quick building of new processing methods directly within the interface.

Integration Algorithms and Productivity

• Includes integration algorithms MQ4 and advanced SignalFinder to generate reliable integration results with reduced manual intervention.
• Designed to reduce tedious manual tasks and help analysts maximize productivity by automating integration processes.
• Supports creation of new quantitation methods with user control over integration parameters.

Multi-Application Data Processing

• Processes MRM, UV, ADC, and full scan data types within a single software environment.
• Supports UV/DAD and ADC data alongside mass spectrometry data.
• Includes usability features that speed data review and comparisons for quality assessment, particularly useful for protein and peptide quantitative workflows and high-multiplexing assays.

Regulatory Compliance and Audit Trail

• Provides a link with Watson LIMS, described as the most widely used LIMS system for regulated bioanalytical laboratories, with a GLB/CFT compliant connection for secure and compliant results transfer.
• Includes an audit map editor that allows administrators to pre-define reasons for changes and enable electronic signatures.
• Grouped audit events reduce the number of electronic signature prompts, improving efficiency during data review.
• Tracks and maintains traceability of multiple event changes to integration methods.
• Reviewers can view data before and after an auditable change using linked data review and audit trail view panes.
• Supports precise and efficient auditing features to maintain lab compliance.

MultiQuant software integrates with Watson LIMS for regulated bioanalytical environments and is part of the broader SCIEX software ecosystem, which also includes SCIEX OS software, LipidView software, and SWATH Acquisition 2.0. The software is available in both research-use-only (RUO) and MD (medical device) variants, as reflected in separate end-user license agreements and release documentation.