MS Software Suite

Bruker's MS Software Suite is a collection of mass spectrometry data analysis tools designed to support a broad range of research applications, including proteomics, metabolomics, lipidomics, glycobiology, biologics characterization, MS imaging, and polymer analysis. The suite integrates with Bruker mass spectrometry instrumentation and is intended for both specialist researchers and routine laboratory users. All products are for research use only and are not intended for clinical diagnostic procedures.

Each software tool in the suite addresses specific analytical workflows, providing automated data processing, compound identification, and results visualization. The tools are designed to work with data from various instrument types and acquisition modes, including MALDI, ESI, PASEF, and TIMS-based platforms.

Proteomics and Structural Biology Software

• DeutEx is an HDX-MS data analysis tool that performs automated deuteration calculations and provides visualization tools for analyzing protein structural and dynamic data across the full HDX-MS workflow.
• Bruker ProteoScape™ (BPS) is a combined hardware and software proteomics data analysis platform that supports real-time data streaming and system suitability monitoring. It covers dda-PASEF workflows (including de novo sequencing via BPS Novor) and dia-PASEF workflows using TIMS DIA-NN and TIMScore for improved false discovery rate determination. It is available for existing and new timsTOF customers.
• OmniScape™ supports top-down proteomics with tools for proteoform verification and identification. The OmniWave™ algorithm is used for analysis of congested MSn spectra and fragment annotation. It includes de novo sequence tag generation for homology-based identification of unknown proteins, modification localization workflows, and the ability to combine data from multiple instrument types (e.g., MALDI and ESI) and fragmentation modes.

Glycobiology and Glycoproteomics

• GlycoScape™ provides real-time glycopeptide results for glycobiology research. It uses the GPU-powered ProLuCID algorithm for peptide identification and the Myriad algorithm for glycan composition analysis, enabling it to keep pace with glyco-PASEF acquisition speeds. GlycoScape™ is bundled with Bruker ProteoScape™ as part of the ProteoScape Package.

Metabolomics, Lipidomics, and Phenomics

• MetaboScape® is an all-in-one software suite for discovery metabolomics, lipidomics, and phenomics. It incorporates the T-ReX® algorithm family along with statistical tools and CCS-aware compound identification workflows. It is designed to help users identify and contextualize drugs, metabolites, lipids, and glycans within a biological framework.
• Metabolomics Spectral Libraries are tailored spectral libraries that support compound identification in metabolomics workflows.

MS Imaging

• SCiLS™ Lab is a software platform for mass spectrometry imaging data, supporting data from multiple major MS vendors. It enables comparative sample analysis for applications in pharmaceutical drug development, tissue-resolved biomarker research, and translational pathology research, including use as a complement to immunohistochemistry.
• SCiLS Pro is an optional feature module extending the SCiLS package with advanced processing and analysis capabilities for MS imaging data, available as an annual subscription license.

Biologics Characterization

• BioPharma Compass® provides automated characterization of biologics through a wizard-driven, workflow-based interface. It is designed to be accessible to both mass spectrometry experts and routine users.

Screening and Quantitation

• TASQ® (Target Analysis for Screening and Quantitation) is a turnkey solution for MS-based automated screening, confirmation, and quantitation of hundreds of target compounds across large sample batches.

Polymer Analysis

• PolyTools is designed for use with MALDI TOF MS instruments and provides data processing for polymer structural analysis, supporting synthesis and quality control workflows. Results can be generated within minutes. PolyTools 2.0 is available for purchase through the Bruker Store.

LC-MS System Monitoring

• TwinScape™ allows users to create a digital representation of an LC-MS system or key parameters to monitor system performance. It supports proactive monitoring via a web application accessible remotely.

Bruker provides support for the MS Software Suite through its LabScape Services, which includes a dedicated helpdesk, maintenance agreements tailored to individual customer requirements, and training courses offered through Bruker Daltonics training centers. Selected software products, including PolyTools and SCiLS Pro licenses, are available for direct purchase through the Bruker Store.