MarketScan Real-World Evidence

MarketScan Real-World Evidence, offered by Merative, is a platform providing access to real-world datasets, analytics tools, and expert research services for generating evidence used in regulatory submissions, health economics outcomes research (HEOR), and epidemiology studies. It is designed for life sciences companies, payers, academic institutions, and government agencies that need research-grade data to support clinical, commercial, and policy decisions.

The platform is built around a portfolio of fully adjudicated closed claims data sourced from US payers, covering actual costs and longitudinal patient views. More than 4,500 peer-reviewed publications have relied on MarketScan data, and the platform supports studies ranging from FDA regulatory submissions to post-approval requirements and disease surveillance.

Core Data Characteristics

• Employer-sourced claims data from payers across the US
• Fully adjudicated closed claims providing actual cost information
• Longitudinal patient-level views enabling long-term follow-up across multiple years
• Complete and representative data designed to minimize bias and increase confidence in research findings

Key Research Capabilities

• Regulatory submissions: Large-scale, fully adjudicated closed claims data supports scientifically robust reporting to regulatory bodies, including FDA clinical trial and post-approval requirements.
• HEOR: Experts connect actual cost data to treatment patterns and health outcomes, helping identify gaps and demonstrate the value of treatments.
• Epidemiology research: Complete and representative data supports exploration of burden of illness and treatment patterns, with reduced bias and increased research confidence.

Analytics and Tooling

• No-code application for data analysis, enabling teams to work without requiring programming expertise
• Scalable cloud environment hosted on Snowflake, reducing deployment time and costs
• Treatment Pathways analytics tool for rapidly making sense of large data volumes and creating patient cohorts for further exploration
• Supports team collaboration through shared cloud-based workflows

Expert Research and Analytics Services

• Access to specialists with experience in epidemiology, regulatory approvals, and HEOR
• Support for expediting the regulatory submission process
• Assistance with post-marketing authorization studies using advanced data access
• Guidance available for designing and executing regulatory-grade studies

Who the Platform Serves

• Life sciences companies: Demonstrating clinical and commercial value of treatments and meeting FDA regulatory requirements
• Payers: Understanding cost, utilization, and prevalence of healthcare services across US geographic areas
• Academic institutions: Developing reliable insights for sophisticated research questions using research-grade data
• Government agencies: Informing decisions on economic impact, disease surveillance, and industry standards

Data Linking and Integrations

• Collaboration with Veradigm to produce a Linked Claims and EHR Database, combining claims data with electronic health record data
• Advanced data linking capabilities to support deeper analysis and decision-making
• Data is readily available on Snowflake's cloud infrastructure for immediate access

MarketScan operates as a single source for data, expert services, and evidence generation. The platform supports the full research workflow from initial data access through analysis and regulatory submission, with resources including whitepapers, webinars, podcasts, and case studies available to support users across research domains.