LiveDesign for Biologics

LiveDesign for Biologics, developed by Schrödinger, is a flexible, cloud-based informatics and analysis environment designed to serve as a digital biologics design and discovery lab. It brings together experimental and computational data, cutting-edge modeling tools, and collaborative decision-making technology into a single unified interface, supporting a broad range of biological therapeutic modalities.

The platform is purpose-built for biologics discovery teams seeking to streamline workflows, reduce data fragmentation, and accelerate the identification of top candidates. By centralizing access to all project data — from sequence and structure to experimental results and in silico predictions — LiveDesign enables teams to work more efficiently and make better-informed decisions at every stage of discovery.

Centralized Data Management

• Break down data silos by consolidating in vitro and in silico data into a centralized federated data platform
• Connect all project data spanning sequence, structure, and experimental results in one accessible environment
• Track decisions and streamline communication across all stages of common biologics discovery workflows, including multi-hit triage and model-driven predictions

Collaborative Decision-Making

• Crowdsource ideas and interactively refine design strategies with colleagues anytime and from anywhere
• Increase project efficiency by securely and easily sharing data between internal teams and external partners
• Build live data dashboards tailored for design, analysis, and collaborative review

In Silico Discovery and Computational Tools

• Fully integrate computational modeling execution, delivery, analysis, and 3D visualization directly into project workflows
• Flexibly develop and explore emerging AI and machine learning technologies through an agnostic snap-in/snap-out API framework
• Identify top candidates faster by embedding predictive modeling capabilities alongside experimental data

Live Data Dashboard Capabilities

• Live data sharing across teams and collaborators
• 3D visualization of biological structures and models
• Customized styling of data views and dashboards
• Biologic format recognition for relevant molecular representations
• Integration of experimental data alongside computational predictions
• Sequence analysis tools embedded within the platform

Related Computational Technologies

• BioLuminate — a comprehensive modeling platform for biologics discovery
• PIPER — a state-of-the-art protein-protein docking program
• Prime — a powerful solution for accurate protein structure prediction
• Desmond — a high-performance molecular dynamics engine offering high scalability, throughput, and scientific accuracy
• FEP+ — high-performance free energy calculations for drug discovery

LiveDesign for Biologics is delivered as a cloud-based platform, enabling access from anywhere. Schrödinger supports users through online certification courses, tutorials, quick start guides, videos, documentation, and dedicated software support to ensure successful deployment and adoption across discovery teams.