StackWave Affinity

StackWave Affinity™ is a comprehensive biologics R&D platform designed from the ground up for biotechnology and pharmaceutical discovery teams. Unlike systems that bolt incomplete toolsets onto an ELN or chemical registry, Affinity provides native, end-to-end support for the entire biologics discovery and development process — from library generation and target identification through to lead characterization and preclinical study initiation.

Affinity eliminates the need for multiple disconnected software licenses by consolidating sequence analysis, project and campaign management, integrated inventory and ELN, custom plotting and reporting, built-in animal studies, and assay data ingest into a single unified solution. Every plasmid, protein, cell, and sequence generates a complete read-out of properties, assay data, inventory, and associated information, while also collecting scientists' comments to foster ongoing asynchronous collaboration across discovery, production, and analytics teams.

Core Platform Capabilities

• Collaborate: Facilitates collaboration between discovery, production, and analytics teams across the full research workflow.
• Integrate: Fully integrated coverage from target identification to lead characterization, with no gaps requiring third-party tools.
• Consolidate: Serves as a single source of truth for all assay data generated across programs and projects.
• Analyze: Provides in-depth analysis tools for evaluating and promoting lead antibodies.

Platform Modules

• Planning: Supports goal establishment, alignment, and efficient management of program and project planning and execution, helping organizations streamline operations and enhance productivity.
• Bioregistry: Organizes and centralizes the high volumes of biological data generated in drug discovery, providing a structured foundation for research and therapeutic development.
• Discovery: Supports all therapeutic discovery platforms, managing data and workflow execution to streamline candidate evaluation and enable informed, timely decision-making.
• Molecular Biology: Enables scientists to plan and execute molecular biology workflows in one place — including vector design, cloning simulation, reverse translation of proteins from the bioregistry, chromatogram review, sequence verification, and capture of aliquots and glycerol stocks in integrated inventory.
• Protein Production: Streamlines protein reagent production by managing protein requests, vector construction, protein expression, and quality control, saving time while maintaining high-quality output.
• Inventory: Provides real-time inventory tracking, seamless distribution, and waste reduction to help teams make informed decisions, meet deadlines, and reduce costs.
• In Vivo: Offers user-friendly tools for planning and executing in vivo studies, including management of subjects, treatment groups, and study schedules, as well as dosing tracking, study event logging, and outcome analysis through visualizations and statistical tools.
• ELN: Promotes collaboration and information sharing among research teams, automates routine tasks, ensures better record-keeping, maintains data integrity, and supports compliance with regulatory standards.
• Analysis: Provides bioinformatics tools for sequence analysis and alignment, titration and dose-response tools for determining optimal therapeutic dosage, and built-in NGS tools for identifying and analyzing the most promising clones from discovery campaigns.
• Reporting: Delivers customizable dashboards for real-time monitoring, enabling scientists and managers to track progress, evaluate team efficiency, and identify and promote the most promising leads.

Additional Tools and Integrations

• LabInspector: An integrated asset management product for managing laboratory instruments, scheduling usage, and tracking laboratory issues.
• Supports both in-vitro and in-vivo discovery workflows out of the box.
• Covers high-throughput screening and sequencing, vector design and verification, cloning, reformatting, expression, and characterization.
• Available via demo request or free trial, and accessible via web browser to support remote and distributed team collaboration.

StackWave Affinity™ is trusted by biologics R&D teams at organizations including Scholar Rock, where it is used to collect and compare all data on potential therapeutics in one actionable platform. The system supports workflows spanning from plasmid registration to in vivo study data registration, making it a robust choice for therapeutic discovery teams seeking to improve cross-functional collaboration and data integrity.