Ledger

Ledger™, developed by Simplicis, is an intelligent sample management platform designed to serve as the operational backbone of modern research laboratories. Built for speed, scale, and scientific robustness, it unites data, automation, and insight across every lab process — from inventory and requesting through to fulfillment and reporting. Ledger™ is suited for discovery science, quality control, and automation environments, and is equally effective for single-site teams and global organizations.

Ledger™ transforms the way labs manage samples by eliminating the chaos of disconnected tools, manual records, and legacy systems. Its API-first architecture provides the agility required for diverse R&D ecosystems, enabling real-time collaboration and decision-making across teams, sites, and instruments. The platform supports any sample type, including small molecules, biologics, and tissues, and integrates seamlessly with existing data and automation infrastructure.

Core Platform Capabilities

• Unified inventory, requests, and fulfillment tracking across all lab operations
• Smart logic that adapts to existing workflows and instruments
• Support for any sample type, including small molecules, biologics, and tissues
• API-first architecture enabling seamless integration with data and automation systems
• End-to-end visibility and unmatched control over the full sample lifecycle

Work Hub — Orchestrate Every Task, Seamlessly

• Unified Task Control: Assign, track, and complete all work from a single interface, spanning sites and teams
• Customizable Views: Each user sees exactly the information that matters to their role and responsibilities
• Real-Time Sync: Automatic updates keep all team members aligned and informed at all times
• Data-Driven Insight: Identify bottlenecks before they affect throughput and lab efficiency

Requesting — Request Smarter, Deliver Faster

• Intuitive scientist experience: Scientists focus on outcomes rather than inventory, with no need to understand storage hierarchies or handle inventory manually
• Request templates on the fly: Templates can be created, reused, or adapted instantly to suit evolving needs
• Industry-leading sample security: Sophisticated sample access controls operate across teams and systems
• Cascading workflows: Intelligent logic automatically triggers the next step in a process without manual intervention
• Intelligent validation engine: Automatically applies business logic to select the optimal container, validate data, and provide users with full visibility into what was chosen and why — removing guesswork and manual searching

Fulfillment — Fulfillment Without Friction

• Automated fulfillment: Full instrument and data connectivity, enabling complex systems to be initiated in as few as two clicks
• Standalone fulfillment: Generate the files needed for key benchtop instruments with easy-to-use tools for processing results
• Manual fulfillment: Track every aspect of in-lab operations, including hand pipetting, with full data integrity
• Modular tools: Teams can implement only the capabilities required for their current processes, without unnecessary complexity
• Hardware flexibility: Supports a wide range of hardware environments, from manual workflows to integrated automation and instrumentation, without forcing operational compromise
• Scalability: As processes grow, shift, or become more automated, Ledger adjusts while preserving data continuity, operator ease, and system integrity
• Supported operational processes include weighing, storage systems, benchtop devices, manual processes, liquid handling, and acoustic dispensing

Admin Tools — Configure with Confidence

• Granular role-based access control to manage permissions across teams and systems
• On-the-fly template and rule creation without requiring IT overhead
• Immutable audit trails for every change, supporting compliance and governance
• Fully configurable permissions, workflows, and business rules that enable scientists to stay compliant while moving faster

Integrations — Your Lab, Unified

• Native integrations with leading automation platforms including Tecan, Hamilton, Beckman, and Echo
• Supports both API-based and file exchange connection methods
• Live visibility across automated stores, balances, and liquid handlers
• Compatible with automated stores, integrated platforms, liquid handling systems, other lab devices, and software integrations
• Designed to connect to both current systems and those added in the future, serving as a unified data and process backbone

Ledger™ is deployed by Simplicis Consulting, LLC and has earned strong endorsements from life sciences organizations including Magnet Biomedicine and TRIANA Biomedicines, who cite its ease of use, added value over competing platforms, and the consultative expertise of the Simplicis team. The platform is designed to keep every system in sync and every sample accounted for, regardless of the complexity or scale of the operation.