Simplicis

Simplicis is a life sciences software company specializing in laboratory information management systems (LIMS) designed to unify samples, data, and automation into a single, scalable platform. Founded in Indianapolis, Indiana, and operating since 2007, Simplicis serves global pharmaceutical companies, biotechs, and research organizations, bringing deep domain expertise to the operational challenges of modern scientific discovery. The company's mission is to make high-quality sample data continuously available as a strategic asset for analytics and AI-driven discovery.

At the core of Simplicis's offering is the belief that sample management is not a standalone function but a foundational layer of scientific operations. When data and processes are connected intentionally, organizations reduce risk, eliminate rework, and remove delays that slow discovery. Simplicis focuses on unifying how samples move, how data connects, and how automation fits — supporting modern sample management operations while optimizing how science happens overall.

Ledger™ — The Core LIMS Platform

• Ledger™ is Simplicis's flagship product, built to unify samples, data, hardware, and discovery workflows in a single system that scales with scientific operations.
• Designed to simplify complex sample management, freeing scientists and researchers to focus on breakthroughs while delivering structured, trusted data that fuels AI-driven insight.
• Provides real-time data access and intuitive navigation to eliminate bottlenecks and accelerate discovery.
• Built by engineers who have spent time in the lab, ensuring the platform addresses real daily operational challenges faced by scientific teams.
• Data architecture is designed with the future in mind, built to support large-scale AI initiatives.

Core Capabilities

• Efficiency: Maximizes productivity through real-time data access, eliminating workflow delays and bottlenecks across laboratory operations.
• Flexibility: Ledger's intuitive features are designed to meet each laboratory's unique sample management requirements, adapting to diverse scientific workflows.
• Advanced Automation: Streamlines requesting, tracking, and fulfillment with automated tools engineered for unparalleled accuracy throughout the sample lifecycle.
• Integrated Ecosystem: Ledger seamlessly integrates with a wide range of industry-leading hardware partners, enabling cohesive lab environments.

Company Background and Team

• Simplicis was co-founded by Bryan Wrench (Co-Founder & CTO) and Heather Colvan (Co-Founder & COO), both of whom bring deep expertise in samples, data, automation, and scale shaped through close collaboration with industry leaders.
• The team's experience comes from living the operational challenges inside modern labs and translating those realities into systems that work.
• Simplicis prioritizes long-term credibility over short-term features, listening closely and designing deliberately to support science today and as it evolves.
• Headquartered at 8520 Allison Pointe Blvd, Suite 220, Indianapolis, IN 46250, USA.

Customers and Validation

• Simplicis works with global pharma, biotechs, and research organizations, including Magnet Biomedicine and TRIANA Biomedicines.
• Customers have noted that Ledger offers more functionality than competing inventory management solutions and is far easier to use.
• Clients highlight Simplicis's added value over competitors at a more attractive price point, as well as the team's excellent turnaround time and deep understanding of compound management.
• Simplicis is recognized for offering proactive improvement suggestions during requirements phases and adapting seamlessly to client feedback.

Simplicis combines Midwest dedication and adaptability — symbolized by the cardinal, Indiana's state bird — with a forward-looking technical foundation. As labs scale and science evolves, Simplicis positions itself as an ever-present partner, delivering a LIMS that keeps samples, data, and automation aligned at every stage of discovery.