IHCExplore

IHCExplore™ is an AI-powered biomarker quantification platform designed for cancer drug developers and clinical researchers working with Immunohistochemistry (IHC) data. By addressing the longstanding challenges of IHC-based scoring, IHCExplore delivers precise quantification of IHC assays at tissue, cellular, and subcellular resolution, enabling more informed treatment strategies and patient stratification.

The platform transforms IHC whole-slide images into deep quantitative insights, extracting key histopathological features to support next-generation biomarker development. IHCExplore characterizes IHC stains and biomarker expression with spatially-contextualized, single-cell resolution, providing a level of analytical detail that goes beyond conventional categorical scoring approaches.

Key Capabilities

• Accelerated biomarker development: Enhances and speeds up the development of AI-enabled biomarkers for novel IHC assays.
• Rapid deployment at scale: Enables continuous, large-scale quantification of biomarkers across study cohorts.
• Deep quantitative measurements: Provides detailed analysis of cell types, stain intensity, and stain completeness.
• Spatial pattern identification: Identifies spatial patterns of stain and expression heterogeneity that are not captured by traditional categorical scores.
• Sub-population discovery: Unveils distinct cellular sub-populations to drive novel biomarker discovery and support standardization of scoring strategies.

Applications

• Biomarker discovery and quantification for oncology research
• Patient stratification to inform treatment strategies
• Development and standardization of IHC assay scoring approaches
• Analysis of expression heterogeneity across whole-slide images

IHCExplore™ is intended for research use only and is not for use in diagnostic procedures. Researchers and drug developers interested in learning more can connect with the business development team directly.