Clinical Genomics Workspace

Clinical Genomics Workspace (CGW) by Velsera is a tertiary analytics and reporting platform purpose-built for clinical NGS laboratories. It supports the entire process of creating a clinical NGS report — from secondary analysis through draft report generation to final sign-out by a medical professional — powered by Velsera's best-in-class Knowledge Base and connected to the Seven Bridges platform for secondary analysis when needed. CGW is disease, assay, instrument, and site-agnostic, making it adaptable to a wide range of laboratory environments and testing programs.

CGW is designed to help laboratories make better clinical reports, faster and with less effort. By combining deep clinical evidence curation, intelligent workflow automation, and seamless system integrations, it empowers labs to deliver precise medical management at every step of a patient's journey — from QA/QC review through therapy recommendations, prognostic and diagnostic information, and clinical trial matching.

Knowledge Base and Clinical Intelligence

• Best-in-class Knowledge Base: Velsera's approach to clinical evidence collection, aggregation, and assembly is focused on a higher standard of quality, richer depth, and better curation than competing solutions, providing laboratories with the most reliable foundation for clinical decision-making.
• Interpretation library: Over 90% of customers have opted in to sharing de-identified variant interpretations, resulting in a library of more than 200,000 interpretations — including contributions from some of the world's leading institutions — that labs can learn from when making their own assessments.
• Complex interpretations: CGW supports complex interpretation scenarios, such as the co-occurrence of gene variants, enabling more nuanced and accurate decisions about patient care.

Workflow Efficiency and Reporting Speed

• Comprehensive end-to-end NGS management: CGW manages secondary and tertiary analysis, sequence data quality review, variant quality review, interpretation, and reporting to electronic health record systems — all within a single seamless workflow.
• Actionable clinical reporting: The platform enables the creation of customizable clinical reports grounded in evidence from trusted sources, helping laboratories focus on delivering optimal therapeutic options and advancing their clinical genomics programs.
• Adaptive learning: As users classify variants within specific disease contexts, CGW learns from those classifications so that the next time the same variant appears in the same context, the default classification is automatically applied, reducing repetitive effort over time.

Integration and Ease of Activation

• Fully integrated platform: CGW utilizes messaging standards and application programming interfaces to streamline the delivery of results and improve data organization and accessibility. It integrates seamlessly with Electronic Health Records (EHR), Lab Information Management Systems (LIMS), and Enterprise Data Warehouses (EDW).
• Structured and PDF export: Once a report is complete, users can export results in structured data formats for EMR/EHR integration as well as in PDF report format.
• Fully supported onboarding: Velsera's in-house teams of clinical, regulatory, and technology experts support laboratories in getting up and running quickly.

Who CGW Is Designed For

• Clinical Diagnostic Laboratories: CGW helps diagnostic labs rapidly establish and grow NGS revenue streams, supporting clinical decision-making alongside validation, revenue cycle management, and access to 20+ LDT and IVD assay options.
• NGS Assay and Equipment Manufacturers: Manufacturers can leverage CGW as part of a fully integrated secondary and tertiary analysis package when bringing new tests or equipment to the clinical market.
• Biotech and Pharma companies: CGW is available as a tertiary reporting component for Companion Diagnostic (CDx) development, helping accelerate test design, regulatory compliance, and laboratory uptake at scale.

CGW supports a broad range of solutions including clinical interpretation and reporting, NGS assay development and expansion, IVD compliance transition, and companion diagnostic development and scaling. The platform is deployable as part of Velsera's broader ecosystem, with optional connections to the Seven Bridges secondary analysis platform, and is backed by regulatory and compliance expertise to support labs navigating FDA clearance processes and other compliance requirements.