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Strand Life Sciences

Clinical NGS reporting, variant interpretation, and genomics software development for precision medicine and oncology diagnostics.

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Overview

Strand Life Sciences is a Bangalore-headquartered company with additional ties to the Bay Area and San Diego that works with customers in precision medicine to solve problems in engineering, bioinformatics, science, and translational medicine involving clinical and omics data. With over 25 years of domain experience, the company employs a team of more than 300 curation scientists, software engineers, testing engineers, bioinformaticians, and clinical researchers, serving clients across academic, pharmaceutical, bioinformatics, biotechnology, and software sectors worldwide.

Strand's work spans three primary solution areas: NGS and PCR diagnostics applications, pharma and biomarker discovery applications, and genomics software application development. The company is compliant with HIPAA and ISO 27001 standards and holds CAP accreditation for its NGS laboratory.

NGS and PCR Diagnostics Applications

  • Assists in speeding up the reporting of clinical NGS tests, covering both somatic and germline variants.
  • Operates a fast, nearly automated platform for small and large oncology panel reporting, built on approximately 10 years of curation and automation work.
  • Has accumulated first-hand experience spanning tens of thousands of reports.
  • Has helped build germline and somatic variant interpretation tools for multiple US diagnostic and device companies.

Pharma and Biomarker Discovery Applications

  • Provides clinical data and bioinformatics solutions to pharmaceutical companies.
  • Supports target discovery, translational research, and clinical research workflows.
  • Delivers real-world data (RWD) insights and multiomics analysis capabilities.

Genomics Software Application Development

  • Helps companies build omics software for managing and analyzing data and metadata across the full range of omics modalities.
  • Assists clients in accelerating software releases and scaling software operations.
  • Provides solutions in data harmonization, precision analytics, platform development, and quality control.

Products and Platform

  • Offers the StrandOmics pipeline, used by clinical laboratories to analyze data from clinical cancer NGS panels and generate clinical reports.
  • The platform has been in active use by customers such as PrimBio Research Institute for over three years for clinical cancer panel analysis.

Notable Customers and Collaborations

  • Has worked with Illumina on bioinformatics consulting and software system maintenance and enhancement.
  • Supported an early-stage multi-cancer detection company in California with maintaining and enhancing critical reporting systems.
  • Assisted a canine diagnostics company with database curation, bioinformatics, and laboratory protocols for an oncology test.
  • Collaborated with an early-stage molecular diagnostics company in San Francisco on characterizing the analytical performance of a gene expression panel.
  • Worked with the University of Chicago on recruiting a clinical cohort of cancer patients and designing and running a liquid biopsy panel.

Compliance, Quality, and Operations

  • Maintains compliance with HIPAA and ISO 27001 internationally recognized standards.
  • Holds CAP accreditation for its NGS laboratory.
  • Applies rigorous internal checks and validation processes across all deliverables.
  • Incorporates AI-based solutions, real-world data insights, and multiomics analysis into its service offerings.

Strand Life Sciences publishes a knowledge hub covering topics including data harmonization, somatic variations, FDA rules on lab-developed tests, microbiome analysis, methylation pipelines, and AI/ML applications in genomics.