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Organoid MEA

Provides real-time, label-free functional readouts from 3D organoid models with high sensitivity and reliability using advanced MEA plates.

Solution by Axion BioSystems
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Overview

The Organoid MEA system delivers label-free, real-time functional readouts from 3D organoid models. Designed with next-generation MEA plates, it offers unmatched sensitivity and reliability, making it ideal for advanced research needs. The Maestro MEA platform is optimized for organoids, providing functional insights and supporting breakthrough 3D innovations.

Key Features:

  • Organoid-optimized plates enhance signal capture and cell attachment.
  • High-sensitivity electrodes record complex activity from models.
  • Noninvasive monitoring allows for continuous recordings without affecting the organoid morphology.

The system is a trusted platform in the field, supported by over 85 publications, making it a leading MEA technology for organoid electrophysiology. The Maestro MEA also features specialized tools, such as flexible electrodes for improved data acquisition in complex biological models.

Additional Innovations

3DMap: This upcoming innovation uses flexible electrode technology to interact directly with 3D organoids, capturing signals across surfaces while maintaining organoid integrity.

  • Flexible electrodes that wrap around organoids.
  • Single well format with 64 electrodes.
  • Features a transparent bottom for better observation.

SpheroGuide: Designed for accurate plating of large organoids, it improves precision and reliability.

  • Includes an integrated placement funnel for easy organoid positioning.
  • Available in a 48-well format with 16 electrodes per well.
  • Utilizes a transparent bottom for optimal visual monitoring.

SpheroHD: This upcoming tool facilitates the plating of small organoids and spheroids.

  • Features high-density electrode spacing at 50 µm.
  • Integrated placement funnel for precise organoid application.
  • 1 well with 4-microwell format, 16 electrodes per microwell, and a transparent bottom.

The Organoid MEA enables researchers to characterize cardiomyocyte function in vitro and measure neural activity from live neural organoids, assisting in cardiovascular disease research, drug development, and safety testing.

Meta

Category
Modeling & Simulation
Field(s)
Imaging & DiagnosticsOmics & Data Analysis
Target user(s)
Bench Scientist / Lab TechnicianClinical / Diagnostic Professional
Tag(s)
Drug Discovery