Multimodal Entity Registration

The Multimodal Entity Registration system offers a comprehensive solution for registering a wide range of therapeutic entities, including natural and non-natural biologics, conjugates, peptides, and small molecules. This unified system supports the evolving landscape of multimodal drug discovery and development.

The system automatically tracks the complete lineage of each entity and its components, utilizing Sapio's materials management to treat samples as first-class objects. The no-code data designer feature allows for easy addition of new entities and attributes, ensuring the registration system evolves alongside scientific advancements.

Biopharmaceutical companies are increasingly focusing on biologics, synthetic peptides, chemically modified oligonucleotides, and antibody-small molecule conjugates, which promise more targeted therapies with enhanced efficacy. The system supports this shift by providing a flexible registration platform that accommodates new types of conjugates, next-generation peptides, and other innovative therapeutic modalities.

Key Features

• Out-of-the-box entity definitions for small molecules, peptides, RNA, DNA, proteins, antibodies, and bioconjugates.
• Flexible registration rules for defining uniqueness and assigning registry IDs based on sequence, HELM string, or chemical structure.
• Integration with Sapio's material management, treating samples as integral parts of the entity lineage.
• Graphical visualization of entity lineage, aiding in comprehensive understanding and IP management.
• Cross-disciplinary collaboration support, allowing chemists and molecular biologists to work seamlessly with a unified source of truth.

The system's extensible data model supports batch loading of various data formats like SDF, HELM, FastA, and Genbank, and offers features like annotated sequence viewing, HELM structure visualization, and advanced search capabilities.

Designed to integrate with electronic lab notebooks (ELNs), the system allows for direct registration from ELNs, ensuring seamless workflow integration and efficient entity management across research projects.