GxP Impedance Module

The GxP Impedance Module, equipped with AxIS Z software, is designed to simplify impedance-based assays in regulated environments. It complies with FDA 21 CFR Part 11, facilitating its use in GMP and GLP laboratories. This software integrates with Maestro systems including Pro, Edge, Z, ZHT, and TrayZ, allowing real-time monitoring and analysis of cellular activities such as proliferation, viability, and interactions without labels.

It provides a straightforward approach to setting up assays, complete with features for experiment execution and data analysis. The module controls experimental settings, provides real-time cellular data, and supports both simple endpoint extraction and in-depth analyses, all while ensuring compliance.

Key Features

• Assay Setup: Automatic acquisition and pre-set analysis configurations simplify setup. It features a built-in Maestro hardware test for accurate impedance measurement, controlled user permissions, and a color-coded plate map that tracks experiments and controls in real time.
• Real-time Data Tracking: The system displays continuous impedance data and comparative analysis across treatment groups. It includes audit trails, an integrated barcode scanner for plate data association, and the ability to monitor experiments remotely via the Maestro Z app.
• Data Analysis Tools: Users can generate cytolysis curves, investigate cellular barriers, and produce publication-ready figures. The Lab Notebook feature within AxIS Z enables live data export to Excel® with integrity checks.

The module supports various life sciences applications such as evaluating antiviral effects, monitoring cell barrier integrity, modeling tumor biology, tracking cell migration, and more. It is an essential component for research that requires compliance and real-time cell monitoring.