BioCircuit MEA Plate

The BioCircuit MEA Plate offers a cutting-edge microelectrode array solution designed for high-quality cellular and electrophysiological research. Available in 24-, 48-, and 96-well formats, these plates are equipped with low-noise recording electrodes, and the 24- and 48-well versions include dedicated stimulation electrodes for enhanced cell stimulation capabilities.

One of the key features is the on-plate spotting guides situated at the bottom of each well. These guides ensure accurate placement of cell droplets over the recording electrodes, resulting in more precise and efficient cell plating.

Key Features

• Accurate cell spotting: Spotting guides ensure cells are well-positioned, optimizing the coverage over electrodes.
• High-quality data: Capture reliable data with industry-leading throughput at a lower cost per well.
• Environmental control: Evaporation-reducing lids with humidity chambers help maintain optimal cell conditions.
• Stimulation capacity: In specific formats, dedicated stimulation electrodes provide superior electrical capability.

The BioCircuit MEA Plate is capable of supporting various applications, from tracking neural development to understanding cardiac function, facilitating advanced research in drug development and disease modeling. Excitable cell types, such as stem cell-derived neurons or cardiomyocytes, perform well across all wells, demonstrating high signal-to-noise ratios.

Enhancing assays with LEAP: The integration with Axion's Local Extracellular Action Potential (LEAP) assay allows for precise action potential recording, providing insights into complex cardiovascular and neural activities.

Applications

• Characterize cardiomyocyte function for drug and safety testing.
• Monitor cardiac differentiation and neural organoid development.
• Elicit and measure electrical activities in tissues and organoids.
• Investigate neural network dynamics using a variety of stimulation techniques.