Xact Software Suite (StatXact, LogXact, Xact PROCs)

Cytel's Xact Software Suite is the world's most comprehensive toolkit for statistical analyses of small, sparse, and missing datasets. Comprising StatXact®, LogXact®, and Xact PROCs, the suite is designed for researchers, statisticians, and data scientists in life sciences and academia who require rigorous, exact inference methods when conventional large-sample approaches are insufficient. As pioneers of small sample methods, Cytel has built the Xact suite to address the unique challenges posed by small and sparse data in clinical and preclinical research settings.

The Xact Software Package offers more than 160 different tests and procedures across StatXact® and LogXact® software, ensuring strict Type I error control for all small-sample methods. The suite includes specialized capabilities that are difficult to find elsewhere, such as exact Poisson Regression, Negative Binomial Regression, and Bayesian methods tailored specifically for small and sparse data environments.

Key Features and Capabilities

• Comprehensive test library: More than 160 tests and procedures are available across StatXact® and LogXact® software, covering a wide range of statistical analysis needs for small and sparse datasets.
• Exact inference methods: Cytel's exact inference methods ensure top-tier, reliable performance trusted by both industry and academia for rigorous hypothesis testing.
• Specialized regression methods: Includes exact Poisson Regression, Negative Binomial Regression, and Bayesian methods specifically designed for small and sparse data — capabilities difficult to find in other software packages.
• Strict Type I error control: All small-sample methods are implemented with strict Type I error control to maintain statistical integrity across diverse trial requirements.
• Rapid and precise hypothesis testing: Enables researchers to conduct hypothesis testing efficiently across a variety of trial designs and requirements, enhancing strategic impact.
• Simplified analysis and interpretation: Complex calculations are streamlined, making findings easier to interpret and share with stakeholders.
• Increased statistical power: The suite is designed to increase confidence in study success by maximizing the power of analyses conducted on small or sparse datasets.

StatXact® 12

• Provides more than 160 tests and procedures, transforming the complex algorithms of modern statistical analysis into accessible, reliable outputs.
• Delivers exact inference methods that are trusted across industry and academic settings for small-sample statistical analysis.
• Supports rapid hypothesis testing with reliable performance for diverse clinical and research trial requirements.

LogXact® 12

• Complements StatXact® by offering additional exact methods and procedures specifically suited to logistic and related regression analyses on small and sparse datasets.
• Contributes to the suite's total library of more than 160 tests, ensuring comprehensive coverage of small-sample analytical needs.
• Maintains strict Type I error control in line with the broader Xact suite's commitment to statistical rigor.

Xact PROCs

• Extends the capabilities of the Xact Software Suite through additional procedures designed to integrate with existing analytical workflows.
• Provides further flexibility for researchers requiring specialized small-sample methods within their data analysis pipelines.

Benefits for Research and Clinical Teams

• Enhanced strategic impact: Supports diverse trial requirements with precise and rapid hypothesis testing capabilities.
• Trusted reliability: Cytel's exact inference methods have an established track record of performance recognized by both industry professionals and academic researchers.
• Ease of use: Streamlines complex statistical calculations and simplifies the communication of findings.
• Confidence in outcomes: Increases the probability of study success by applying statistically sound methods to challenging small-sample data scenarios.

The Xact Software Suite is available for purchase via license through Cytel and is positioned within Cytel's broader portfolio of trial design software solutions. It is particularly relevant for teams working in drug development, clinical trials, and academic research where small, sparse, or missing data present significant analytical challenges requiring specialized statistical methods.