Trial Accelerator

Trial Accelerator is a self-service SaaS platform developed by Phesi, giving life sciences companies direct access to the world's largest clinical trials database containing real-world data. Built on two decades of expertise in simulating clinical trials, it delivers indication-specific predictive modelling to help sponsors optimise protocol design and improve the accuracy, speed, and overall performance of their clinical programs.

The platform is designed for clinical operations teams, R&D leaders, and life sciences organisations seeking a data-driven approach to trial planning. Trial Accelerator offers four dynamic, integrated views — Patient View, Trial Performance View, Country Performance View, and Investigator Site Performance — each targeting a distinct stage of trial design and execution.

Patient View: Create a Digital Patient Profile

• Builds a data-driven understanding of the relevant global patient population using key variables
• Incorporates comorbidity data to reflect real-world patient complexity
• Analyses demographics and diversity across the target population
• Accounts for concomitant medications relevant to the indication
• Applies modal inclusion and exclusion criteria values derived from historical trial data
• Enables accurate modelling of outcomes and patient pathways

Trial Performance View: Simulate Enrollment Cycle Time Predictions

• Simulates enrollment cycle times and identifies the optimum number of investigator sites
• Uses modal design value simulation drawn from similar ongoing or completed trials, including competitor trials, as well as research protocols and amendments
• Helps eliminate avoidable protocol amendments, with potential savings of up to $500,000 and 5.2 months of additional implementation time per amendment avoided

Country Performance View: Identify the Highest Performing Countries

• Ranks countries by phase and indication using real-world data
• Evaluates enrollment performance across geographies
• Measures time to activate sites in each country
• Assesses patient data quality at the country level
• Provides an indication performance score for each country
• Supports accurate recruitment scenario modelling to inform country selection strategies

Investigator Site Performance: Rank KOL and Investigator Performance

• Ranks key opinion leaders (KOLs) and investigator sites by country, indication, biomarker, and phase
• Leverages proprietary statistical models measuring past site activation, patient enrolment, and patient data quality
• Provides performance-based analysis of KOL and investigator sites, including contact details, workload insights, clinical interests, and competitor trial involvement
• Helps identify both existing and emerging global KOLs
• Targets reduction of non-active, non-enrolling sites to less than 10%

Proven Customer Outcomes

• Phesi has worked with leading organisations including Takeda and Sanofi to demonstrate the value of data-driven trial design
• Clients have reported significantly quicker and more cost-effective development timelines through the use of adaptive trial design modelling supported by Trial Accelerator
• Industry leaders describe Phesi as performing systematic analysis of the clinical trial, protocol, and site space to form and test hypotheses — applying learnings to inform new clinical programs or rescue existing ones

Trial Accelerator is delivered as a cloud-based, self-service SaaS platform, making it accessible to global R&D teams without the need for complex implementation. The platform integrates real-world data across all four views, ensuring that insights from patient profiling, trial simulation, country selection, and site performance are connected and mutually reinforcing throughout the trial design and execution process.