TeselaGen Platform
Design-build-test-learn informatics for synthetic biology, from DNA design and assembly to lab automation and AI-driven discovery.
Overview
The TeselaGen Platform is an end-to-end biological R&D solution designed to connect biologists, lab technicians, and bioinformaticians across the full design-build-test-learn cycle. By managing the complete information flow from initial sequence design through laboratory execution, data capture, and machine-learning analysis, TeselaGen eliminates data silos, reduces manual transcription errors, and ensures full traceability from hypothesis to result. The platform is suited for teams ranging from individual researchers to global enterprises working in synthetic biology, protein engineering, and broader life sciences R&D.
At its core, TeselaGen is composed of nine integrated, modular toolkits that can be mixed and matched to fit specific research needs. AI modeling — including the newly introduced Tesela AI agents for library design, protocols, and optimization — enables dramatically accelerated discovery of new materials and engineering of biological systems.
Electronic Lab Notebook
- Centralized experiment planning covering hypotheses through methodologies
- DNA assembly integration with Golden Gate and Gibson support
- Real-time data entry, tracking, and interactive tables
- Cross-team sharing with version control and access management
Molecular Biology
- Visual vector editor with restriction enzyme management
- DNA assembly methods including Gibson, Golden Gate, MoClo, USER, and PCR
- CRISPR guide RNA scoring and automated knock-in design
- Pairwise and multiple sequence alignment, NGS mapping, and Sanger QC
Advanced Molecular Biology
- Intelligent long sequence partitioning for assembly
- Genetic schematic visualization for publications
- Dynamic base-pair-level validation rules
- Inventory cross-referencing to minimize synthesis costs
Registry and Inventory
- Management of DNA, RNA, strains, proteins, enzymes, and cell cultures
- Strain library with plasmid tracking and provenance
- Aliquot and sample management with real-time updates
- Complete biomaterial lineage and audit trails
Freezer and Equipment Management
- Customizable freezer setup with barcode tracking
- Visual mapping for quick sample retrieval
- Centralized equipment service and maintenance records
- Multi-site location management and inventory control
Workflow Management
- Custom workflow builder with atomic-level actions
- Modular, reusable workflow steps
- Automated worklist generation for liquid handlers
- Real-time task tracking and team job assignment
Lab Automation
- Worklist export compatible with Echo, Tecan, Hamilton, and Biomek liquid handlers
- Sequencing QC with automated alignment and variant detection
- Automated sample placement strategies
- One-click export to automation-ready formats
BioShop — Materials Ordering
- Automatic DNA synthesis scoring and compatibility checks
- Instant price estimates for budget planning
- Multi-vendor support including Twist Bioscience and IDT
- Centralized order tracking dashboard with CSV export
Discover — AI and Machine Learning
- Predictive models for phenotypes, titers, and binding affinity
- Generative lead generation for peptide and protein design
- Bayesian optimization for experiment recommendations
- Custom AI model training and deployment
Design and Build Capabilities
- Combinatorial Golden Gate assembly with automated primer design
- Vector editor with real-time sequence visualization
- Automated assembly planning, part sourcing, and protocol generation
- Constraint-based optimization and batch processing tools that scale from single plasmid construction to combinatorial libraries of thousands of variants
Security, Compliance, and Interoperability
- ISO 27001 certified information security management protecting proprietary data and intellectual property
- Comprehensive REST API for seamless integration with existing LIMS, ELN, and data management systems
- FAIR data principles applied across all experimental data — Findable, Accessible, Interoperable, and Reusable — with structured metadata, standardized ontologies, and persistent identifiers
- Visual drag-and-drop Integration Flow Editor for designing and orchestrating complex multi-step workflows without writing code
Product Tiers
- Community: Free tier providing access to core design tools, sequence management, and the TeselaGen community
- Starter: For small teams, including collaborative project spaces, enhanced design capabilities, and API access
- Enterprise: Full platform access with advanced security, single sign-on, audit trails, dedicated infrastructure, and custom integrations
- Catalyst: White-glove consulting and implementation services including custom AI/ML model deployment and outcome-focused delivery
TeselaGen is deployable as a cloud-based solution and is built to integrate into existing laboratory infrastructure. Its combination of ISO 27001 security, FAIR data compliance, open API connectivity, and modular toolkit architecture makes it well suited for both emerging biotech teams and large enterprise R&D organizations seeking to accelerate biological product development.
