Signals Notebook

Signals Notebook, developed by Revvity Signals, is the premier cloud-native Electronic Laboratory Notebook (ELN) trusted by over one million scientists across pharmaceuticals, biotechnology, chemicals and materials, and food, flavor and fragrance industries. As a fully SaaS-based solution, it provides a centralized platform for capturing, organizing, and sharing scientific data, enabling research teams to collaborate more effectively and make data-driven decisions faster — from anywhere, on any device.

Unlike traditional ELNs that rely on server software hosted in the cloud, Signals Notebook is built on a truly cloud-native architecture, delivering automatic updates, effortless scalability, and rapid deployment within weeks rather than months. It features native integration with ChemDraw™ — the industry-standard chemical drawing tool — as well as Spotfire® for advanced analytics, making it the only ELN to seamlessly combine these capabilities in a single platform.

Core Research Data Management Capabilities

• Document experiments using flexible templates, rich text formatting, and embedded multimedia content.
• Organize data with customizable folder structures, tags, and powerful search capabilities.
• Maintain complete traceability through automatic versioning and comprehensive audit trails for regulatory compliance.
• Access work from any device with an internet connection and modern web browser — no VPN or special software installation required.
• Benefit from a rapid release cycle of 10 major updates per year, continuously delivering new features and enhancements.

ChemDraw Integration and Chemical Search

• Automate stoichiometry calculations directly within the notebook environment.
• Utilize multiple structural formats by pasting SMILES strings or dragging and dropping ChemDraw files.
• Search for chemicals using CAS Number, structure, or name with full access to PubChem material safety data sheets.
• Streamline chemical workflows without requiring third-party plugins, unlike traditional ELN solutions.

Real-Time Collaboration Features

• Share notebooks and experiments with granular, role-based permissions controlling who can view, edit, or approve content.
• Comment, review, and approve entries with electronic signatures.
• Use @mentions and notification systems to keep team members informed of updates and changes.
• Track project progress through integrated dashboards and version control that records all changes.
• Enable seamless collaboration whether team members are in the lab, working remotely, or distributed across the globe.

Inventory Management

• Track chemicals, reagents, and samples directly within the notebook without switching between systems.
• Scan barcodes to capture materials quickly and accurately.
• Locate inventory instantly with built-in location tracking and complete material traceability.
• Stay ahead of supply shortages with automatic low-stock alerts.

Instrument and Ecosystem Integrations

• Connect analytical instruments using Signals DLX for automated data capture, parsing, and organization directly into Signals Notebook — eliminating manual data entry.
• Integrate with Spotfire® for advanced analytics and data visualization.
• Support LIMS integration for sample management workflows.
• Use open APIs to connect with ERP systems and other enterprise research tools, enabling seamless data flow across the entire R&D technology stack.

Security and Compliance

• SOC 2 Type II certified with independently audited security controls to meet the highest industry standards.
• Built on enterprise-grade AWS infrastructure with encryption at rest and in transit to protect intellectual property.
• Role-based permissions and multi-factor authentication ensure only authorized users access sensitive research data.
• Supports 21 CFR Part 11 compliance requirements with electronic signatures, audit trails, and validation documentation.
• Provides prebuilt IQ, OQ, and PQ templates designed specifically for regulated pharmaceutical and biotech environments.
• Expert validation support available to streamline deployment and reduce compliance effort.

Signals Notebook vs. Traditional ELN Solutions

• Cloud-native architecture versus server software that is merely cloud-hosted.
• Native ChemDraw integration versus reliance on third-party plugins.
• Real-time collaboration versus lock-based, sequential access models.
• 10 rapid releases per year versus annual or biannual update cycles.
• Automatic, seamless updates versus scheduled maintenance windows requiring IT intervention.
• No infrastructure required versus the need for dedicated IT infrastructure.
• Rapid deployment in weeks versus month-long implementation timelines.

Expanding Signals Notebook with Signals One

• Signals One builds on the Signals Notebook foundation to add AI-enhanced workflows and user experience features.
• Provides structured data handling and deeper SAR (structure-activity relationship) insights for decision making.
• Includes integrated analytics capabilities not available in the standard Signals Notebook offering.
• Represents a comprehensive solution unifying the ELN with advanced analytics and enterprise data management.

Signals Notebook is available as a free trial with full access to ChemDraw integration, collaboration tools, and cloud-native capabilities, as well as a Standard Edition available for immediate purchase. Implementation is supported by onboarding resources, training materials, and migration assistance to ensure a smooth transition from paper notebooks or legacy ELN systems.