Seven Bridges Platform

The Seven Bridges Platform, developed by Velsera, is a Trusted Research Environment (TRE) designed for bioinformatic analysis and pipeline development. It bridges research and clinical diagnostics seamlessly, empowering precision medicine by bringing cloud-optimized algorithms and proprietary tools directly to where the data lives. Trusted by over 18,000 researchers from more than 50 countries and running 650,000+ analyses per quarter, the platform serves a broad range of users including biotech and pharma companies, non-profits, government agencies, clinical diagnostic laboratories, and NGS assay and equipment manufacturers.

The platform is purpose-built to support two primary domains: drug discovery and clinical diagnostics. For drug discovery teams, it provides a scalable, highly secure cloud-based environment that accelerates the use of biomedical data across the full drug discovery life cycle. For clinical diagnostic laboratories, it supports secondary NGS analysis to streamline workflows and deliver reliable, reproducible results.

Drug Discovery Use Cases

• Biomarker discovery
• Target identification
• Lead optimization
• Clinical trial optimization

Clinical Diagnostics Use Cases

• Variant calling
• Assay development
• Report generation

Security and Compliance

• Seamless and secure data access — the cloud-agnostic platform brings analytics to the data, increasing analysis speed and reducing time to results, with robust provenance tracking for detailed auditability and access control, including integration with dbGaP.
• Industry-leading compliance standards — the platform is compliant with GDPR, FedRAMP (moderate), FDA, AICPA SOC 2, dbGaP, and ISO 9001, 27001, 27017, 27018, and 27701.

Efficiency and Flexibility Features

• Flexible infrastructure — the platform adapts to workload demands, providing efficient compute and storage solutions while managing costs effectively and ensuring reliable performance without unnecessary overhead.
• Predictable costs — built-in cost predictor tools allow teams to estimate compute costs ahead of time and manage compute budgets proactively.
• Extensive out-of-the-box and customizable resources — access to 950+ tools and workflows, 150+ data sources, 48 petabytes of data, and data covering 1.7 million patients, enabling multi-omics data organization, exploration, and analysis.
• Low and no-code analytics — a suite of customizable, no-code visualization tools including an interactive genome browser for collaborative investigations, as well as RStudio and JupyterLab coding environments for interactive analysis.
• RHEO automation — built on the Seven Bridges Platform, RHEO minimizes manual steps required to set up, run, and conclude analyses. Key highlights include 80% fewer lines of code, 100% reproducibility through automation, and push-button automations that eliminate manual setup, metadata curation, and compute management.

Notable Platform Deployments

• Cancer Genomics Cloud (CGC) — focused on uncovering new insights into cancer genomics.
• CAVATICA — designed to accelerate pediatric research and discovery.
• BioData Catalyst — providing access to leading heart, lung, blood, and sleep data.

Solutions Supported

• Analysis and bioinformatics — supported by in-house bioinformatics and science teams to help researchers cut through complex clinical-genomic data and accelerate breakthroughs.
• Clinical and omic data unlock — harmonizing scattered, siloed, and unstructured clinical-genomic information to make it available for novel discovery work.
• NGS assay development and expansion — creating, integrating, hosting, and deploying custom-developed NGS analysis pipelines, with validation, regulatory support, and Revenue Cycle Management support.
• IVD compliance transition — assisting labs in navigating the FDA clearance process for new assays and existing Laboratory Developed Tests (LDTs), including optional tertiary reporting.
• Companion diagnostic development and scaling — partnering to design, develop, and deploy Companion Diagnostic (CDx) pipelines, with support for validation, regulatory compliance, and reimbursement enablement.

The Seven Bridges Platform is a cloud-agnostic solution deployable across major cloud providers, with integrations including dbGaP and optional tertiary CGW reporting for fully integrated secondary and tertiary analysis packages. Velsera's in-house scientists and bioinformatics teams provide hands-on support to help organizations across pharma, government, academic, and clinical settings maximize the value of their genomic and clinical data assets.