Progressive GRT

Progressive GRT (Global Regulatory Triage) is a software solution developed by Nextrove for managing and processing adverse event data from regulatory authorities' databases. It is designed for pharmacovigilance and drug safety teams operating in complex global regulatory environments, supporting automated triage, case download, and transmission of adverse event information to safety systems.

The application is accessible directly from within a user's existing safety application, reducing the need to switch between systems. It can connect directly to regulatory agencies' databases to automatically download files, and it also operates on previously downloaded files. Progressive GRT can function as a source data channel for Progressive Intake, Nextrove's intake management product.

Case Management Capabilities

• Automated and intelligent case management for adverse event data
• Automatic case download from regulatory agencies' databases when a direct connection is available
• Intelligent case triage to identify and prioritize relevant adverse event cases
• Advanced search and triage capabilities with a dedicated search layout
• Triage of newer case versions to ensure safety teams work with the most current information

Features and Technical Capabilities

• Comprehensive case review functionality
• Efficient reporting and data management
• PDF generation for case documentation
• E2B R2 and R3 file generation for regulatory submissions
• Support for multiple file formats
• Optimized performance for speed and flexibility
• Integration with safety systems

Deployment and Compliance Characteristics

• Lightweight deployment model
• Secure architecture
• Audit-ready design
• Fully validated in accordance with regulatory requirements

Progressive GRT is positioned for organizations managing adverse event data from multiple regulatory agencies, with a focus on reducing manual administrative effort, maintaining compliance, and integrating with existing safety system infrastructure.