PAS-X MES Suite

The PAS-X MES Suite by Körber is a world-leading Manufacturing Execution System (MES) designed for the pharmaceutical, biotech, and cell and gene therapy industries. It digitally controls, monitors, and documents production processes in real time across the entire manufacturing lifecycle — from process development and commercial production through to packaging. PAS-X is used by more than 50 percent of the top 30 companies in the industry globally, as well as by many mid-sized manufacturers, and Körber has been recognised multiple times as a "Leader" in the Gartner® Magic Quadrant™ for Manufacturing Execution Systems.

The suite helps organisations reduce error rates and manufacturing costs, shorten time-to-market, and increase overall operational efficiency. PAS-X can be implemented out of the box and integrates seamlessly with surrounding IT systems via standard interfaces. It combines over 30 years of industry expertise with modern IT technologies, supporting cloud-native and SaaS operations as well as powerful data transparency and analytics capabilities.

Key Capabilities of the PAS-X MES Suite

• PAS-X Scheduler: Synchronises operational workflows with supporting activities, integrating planned tasks with the actual state of production to support a schedule-oriented operating model.
• PAS-X Weighing & Dispensing: Enables recipe-accurate, digital weighing and dispensing of input materials, making dosing and weighing processes more precise, efficient, and error-proof.
• PAS-X Electronic Batch Recording: Simplifies complex manufacturing instructions through digital Master Batch Records and ensures safe, guided execution via Electronic Batch Recording.
• PAS-X Equipment Management: Provides comprehensive management and monitoring of cleaning processes and equipment states, covering all plant-related requirements in pharma and biotech.
• PAS-X KPI/OEE: Delivers accurate and transparent key performance indicators to continuously improve Overall Equipment Effectiveness (OEE).
• PAS-X Track & Trace: Combats pharmaceutical counterfeiting through serialisation, enabling regulatory authorities and customers to trace the identity and journey of medicinal products at any time.

PAS-X MES 3.4 — NextGen Cloud and AI-Powered Manufacturing

• Web-based, scalable platform with an intuitive user interface and AI support.
• Intelligent tools for deployment, monitoring, and long-term lifecycle management.
• NextGen Shopfloor (NGS) concept supporting equipment-specific Master Batch Records (ESPs) covering order execution and review.
• Modern, responsive user experience across all device types.
• Order activity capture is up to 3× faster; access to exceptions data is up to 5× faster.
• Planned infrastructure cost reduction of 30%.
• ERP integration effort reduced by 15%.
• System throughput with multi-instance increased by 30–50%.
• Fully automated upgrades and minimal risk of unplanned downtime.
• Seamless migration support from pre-assessment through to go-live, with dedicated services and automation tools to significantly reduce migration effort.

Cloud Deployment with AWS and Azure

• Flexible cloud implementation approach supporting customers at any stage of their cloud journey.
• Partnerships with Amazon Web Services (AWS) and Microsoft Azure to ensure security, reliability, and high availability.
• Options include private cloud hosting or a fully managed Software as a Service (SaaS) solution.
• Proven track record of delivering GMP-compliant MES solutions in the cloud.
• Novo Nordisk, as an early adopter, has deployed PAS-X MES 3.3 on Azure to accelerate MES implementation across global sites, using it as the centrepiece of its Pharma 4.0 digital ecosystem.

Business Benefits

• Faster time-to-market: Up to almost two-thirds reduction in time-to-market for new products.
• Right First Time: 98% error-free production from the first run.
• Full regulatory compliance: Meets all requirements of relevant approval authorities.

Complementary Suites

• PAS-X Savvy Suite: Accelerates product commercialisation by enabling real-time management, visualisation, and analysis of bioprocess technology data.
• PAS-X Content Suite: Prepares PAS-X MES quickly for specific industry segments — including pharma, biotech, and cell and gene therapy — using pre-parameterised content to support individual system configuration.

PAS-X MES is available for on-premise or cloud deployment and supports integration with all major surrounding IT systems via standard interfaces. Körber's global PAS-X user community — the largest MES community in the pharma and biotech industry — actively participates in the ongoing development of the software, ensuring it continuously reflects best practices from across the industry. Körber provides comprehensive consulting, migration, and lifecycle services to support customers throughout implementation and beyond.