Participant Engagement

YPrime's Participant Engagement solution is a built-in capability embedded within the YPrime eCOA platform, designed to help sponsors and CROs reduce participant dropout risk, minimize participant burden, and protect data integrity throughout the clinical trial lifecycle. Rather than treating engagement as a standalone add-on, YPrime approaches it as a foundational element of trial execution — grounded in behavioral research, human-centric design, and real-world trial experience.

Participant dropout is a significant challenge in clinical research: approximately 30% of patients drop out of trials, each replacement costs an estimated $19,000, and 80% of trials are delayed by at least one month as a result. YPrime's integrated engagement strategy directly addresses these risks by keeping participants informed, prepared, and supported at every stage of their study participation.

Core Engagement Philosophy

• Engagement is embedded directly into the eCOA assessment experience, eliminating the need for additional apps, portals, or fragmented workflows
• Interactions are designed using behavioral science principles to reduce anxiety, encourage timely completion, and support sustained participation over time
• Multilingual support, clear navigation, and thoughtful notifications accommodate diverse participant populations across global regions
• By integrating engagement into the clinical trial workflow, studies fit more naturally into participants' daily routines, supporting adherence and retention
• Human-centric design and research-informed decision-making ensure that clear, relevant information is delivered at every stage of the trial

YPrime Participant Hub

• Built directly within the YPrime eCOA platform, the Participant Hub provides participants with centralized access to study guidance, upcoming activities, and key resources throughout the trial
• At the center of the experience is the "For You" Page, which organizes visit schedules, study information, and protocol guidance within the eCOA app
• Centralized Study Information — visit schedules, study explanations, and key resources consolidated in one location
• Task Visibility — a clear view of upcoming assessments and study activities so participants always know what is expected of them
• Protocol Guidance — FAQs, training materials, approved study documentation, and additional support resources

Platform-Wide Engagement Capabilities

• Participant engagement features span both eConsent and eCOA, leveraging user-friendly design, personalization, and behavioral science to drive patient retention and adherence
• The platform supports informed participation, operational consistency, and inspection-ready execution across global trials
• YPrime's broader clinical trial technology suite — including eConsent, IRT, and eCOA — works together to support participants, sites, and sponsors throughout the study lifecycle
• YPrime was recognized as a 2024 Trailblazer in Patient Engagement, reflecting its commitment to advancing participant-centered trial execution

YPrime's Participant Engagement solution is delivered as an integrated component of its eCOA platform, supporting global, multi-regional trials with multilingual capabilities and a design philosophy centered on reducing burden for all stakeholders. By combining technology, behavioral science, and operational expertise, YPrime enables sponsors and CROs to run clinical trials with greater certainty and confidence.