Monomer

Monomer Bio is a laboratory automation software platform purpose-built for cell biology research. Designed by cell biologists, roboticists, and engineers, Monomer enables life sciences teams to develop and optimize high-quality in vitro disease models by automating cell culture workflows using readily available hardware and instrumentation. The platform is suited for research organizations looking to increase throughput, reduce biological noise, and accelerate the pace of discovery.

Monomer integrates advanced workflow automation, real-time monitoring, and data analysis tools into a cohesive system that connects directly to standard lab instruments. By combining AI-driven scientific agents with fully automated workcells, Monomer empowers labs to maintain cells at scale, run mission-critical experiments, and make faster, more impactful decisions.

Core Platform Capabilities

• Scientific Agents: Grow and annotate complex tissues through a responsive UI backed by AI that learns from every experiment, enabling increasingly intelligent automation over time.
• Autonomous Workcells: Execute workflows on fully automated workcells using a multi-day scheduler with well-level control and consumable tracking.
• Reproducible Tissues: Increase consistency, reduce biological noise, and eliminate single points of failure on key capabilities through digitized production workflows.

The Monomer Stack

• Biology: Maintain cells at scale so research teams can focus on designing and running mission-critical experiments rather than routine culture tasks.
• Automation: Connect to standard lab instruments to create automated protocols that multiply throughput across the laboratory.
• Data: Continuously monitor cell cultures, track changes over time, and make historical well data easy to retrieve and reuse.
• Insights: Access a real-time feed of analyzed culture data to simplify cell maintenance decisions and prioritize the most impactful actions.

Workflow Steps

1. Monitor: Track changes in plates via integrated imaging to gain real-time insight into hundreds of live samples simultaneously.
2. Record: Generate, organize, and share cell line and culture data directly from lab instruments.
3. Interpret: Plot metrics of interest to identify trends and structure imaging data for deep learning applications.
4. Act: Update protocols and take action in response to changing growth conditions or experimental readouts.

Application Areas

• Cell Culture: Develop and optimize protocols for adherent, suspension, and 3D culture workflows, including media composition and feeding schedule optimization.
• Stem Cell Differentiation: Consistently develop organoids using 2D or 3D culture models by growing dozens of stem cell and tissue types in parallel and at scale.
• Cell Engineering: Streamline the generation of novel cell lines with tools that track critical characteristics such as transfection efficiency and monoclonality.

Monomer Bio guides clients through the full journey of lab automation, from initial consultation and instrument integration to data analysis and experimental design. The platform is deployed from the company's base in San Francisco, CA, and is trusted by leading life sciences organizations seeking to bring infrastructure-grade reliability to cell biology research.