MES

Pharmasoft's MES – Manufacturing Execution System is designed to act as the digital backbone of pharmaceutical production environments. It connects shop-floor operations with enterprise systems, providing a real-time view of manufacturing activities, resources, and equipment performance. The system is intended for pharmaceutical and biotech manufacturers seeking to replace manual production processes with automated, GMP-compliant digital workflows aligned with Pharma 4.0 requirements.

MES acquires data automatically from PLCs, SCADA systems, DCS controllers, IoT sensors, and other automation layers via standard industrial communication protocols. This ensures that production records accurately reflect actual operations, reduces manual data entry, and supports dynamic scheduling, early bottleneck identification, and optimized resource utilization.

Digital Batch Execution and Right First Time Manufacturing

• Guided, SOP-driven workflows with validated process checks at each step
• Automated calculations to eliminate manual errors during batch execution
• Integrated electronic signatures for step-by-step approvals
• Real-time operator prompts for deviations and exceptions as they occur

Equipment Lifecycle and Logbook Management

• Unified scheduling for calibration, preventive maintenance, and breakdown maintenance
• Equipment usage tracking with digital logbook entries
• Automated alerts for upcoming or overdue maintenance and calibration events
• Full equipment history including service records and attachments

Real-Time Visibility and Compliance Readiness

• Live monitoring of batch progress and overall production status
• Review-by-exception functionality to accelerate batch release cycles
• Time-stamped audit trails for every action and data point
• GMP-compliant execution aligned with regulatory expectations

OEE Calculation and Production Intelligence

• Automatic calculation of Overall Equipment Effectiveness (OEE) using the formula: Availability × Performance × Quality
• Real-time data capture from equipment feeds OEE metrics directly
• Real-time production monitoring dashboards to identify and resolve bottlenecks
• End-to-end visibility into equipment usage, batch progress, and improvement opportunities

Dynamic Production Scheduling

• Real-time visibility into equipment availability, material readiness, and resource allocation
• Dynamic scheduling adjustments in response to production changes or equipment issues
• Resource coordination to optimize manufacturing throughput
• Streamlined batch workflows to remove documentation delays and manual coordination gaps

Reported Performance Benchmarks

• 10–20% increase in Overall Equipment Effectiveness (OEE)
• 80% reduction in manual data entry effort
• 15–30% reduction in unplanned downtime
• 5–15% reduction in batch cycle time

Pharmasoft MES is part of a broader suite of operations modules that includes Electronic Batch Manufacturing Records (softBMR), calibration and maintenance management (eCalPM), and electronic equipment logbooks (E-Log). It is positioned for regulated pharmaceutical manufacturing environments and supports integration with existing plant infrastructure through standard industrial communication protocols.