HALO Link

HALO Link is an enterprise-grade, AI-ready image management system (IMS) developed by Indica Labs, designed to serve as the backbone of digital pathology infrastructure for life science organizations. It provides secure, anywhere, anytime access to whole-slide images, metadata, and analysis results through a modern, browser-based platform built for efficiency, collaboration, and scalability across multiple sites and user groups.

Suitable for pharmaceutical companies, research institutions, and clinical laboratories, HALO Link combines flexible study-centric data organization, powerful search, and seamless integration with leading image analysis tools — including Indica Labs' own HALO® and HALO AI platforms — to accelerate discovery across oncology, immunology, infectious disease, metabolism, and beyond.

Core Platform Capabilities

• Scalable, modern architecture designed to expand across multiple sites and growing user bases
• Centralized data management for seamless collaboration across teams and institutions
• Scanner-agnostic platform with broad LIS and LIMS compatibility
• Highly interoperable with image analysis platforms and third-party AI solutions via a powerful open API
• Auditing and Good Laboratory Practice (GLP) support for regulatory compliance
• Cloud deployment options available through Indica Labs Cloud Services for secure, scalable, and flexible infrastructure

Advanced Image Viewer and Annotation Tools

• Powerful, intuitive browser-based image viewer supporting magnification changes, brightfield z-stack viewing, and Ergo pan mode
• Fluorescent image visualization with channel histogram and real-time preview of adjustments
• Robust annotation tools including flood-fill and undo-redo functionality
• Annotation manager for creating annotation layers across slides and performing bulk annotation actions
• Interactive markups enabling toggling of visibility for specific cell populations of interest

Study-Focused Data Organization and Search

• Flexible study-based data hierarchies with no limits on organization depth
• Study landing page displaying recently accessed and favorited studies
• Study tree display for smooth navigation of sub-studies
• Custom study and slide metadata fields at every level for task tracking and data organization
• Advanced search using compound metadata criteria with the ability to save and reuse searches
• Search results can be navigated directly or added to a slide tray for selective review

Collaboration Features

• Slide trays for temporarily hosting slides from multiple studies for selective review with collaborators
• Trays include all associated metadata, annotations, and analysis markups
• Intuitive invitation and user group systems for straightforward collaborator access
• Real-time international collaboration supported, as demonstrated in deployments at institutions such as the National Cancer Institute and Fred Hutchinson Cancer Research Center

AI-Powered Image Analysis Integration

• Seamless integration with Indica Labs' HALO® platform for quantitative brightfield and fluorescence image analysis
• Run saved analysis settings or classifier pipelines directly within HALO Link and visualize results in the platform
• Support for deep learning-based classifiers including HALO AI tools such as SlideQC BF for detecting folds and common slide artifacts
• Efficient sorting, filtering, viewing, and analysis of segmented TMA cores
• Open API enabling direct launch and in-platform visualization of results from third-party AI applications

Workflow Automation and Task Management

• Flexible tasks system for organizing workflows and tracking progress and results
• Custom task fields configurable to the specific needs of each study
• Task status updates available directly within the slide viewer
• Sort and filter slides by task status to identify pending, failed, or completed tasks
• Automated ingestion of new images and data from slide scanners as soon as they are acquired
• Barcode parsing for automatic import of relevant metadata

Data Visualization and Figure Creation

• Diverse plotting tools including heatmaps, scatter plots, violin plots, and box and whisker plots for evaluating trends and performing quality control
• Interactive data points that open slide previews or full slide views on click
• Figure maker feature for acquiring publication-quality figures with control over frames, scale bars, labels, and resolution
• Figures can be saved for later editing or downloaded at a desired image size and resolution

Compliance and Administration

• Compliance Add-on supporting Good Laboratory Practices (GLP) SOPs with exportable study and system-wide audit trails
• Reason for change capture and a viewing-only mode for regulatory requirements
• Fully featured Admin dashboard for managing user permissions, configuration details, and system-wide metadata fields
• View login attempts and review active jobs from the admin interface
• Diagnostic Monitor providing insights into image viewing performance

Migration and Integration Services

• Dedicated Integration and Migration Services team supporting legacy IMS migrations to HALO Link, including from Aperio eSlide Manager
• Configuration: Acquire database and determine which custom metadata fields will be migrated
• Migration: Configure and run migration scripts
• Quality Control: QC the database and launch the migrated HALO Link database
• Go Live: Customer exploration and final quality control in HALO Link
• Training: Multiple applications-focused sessions tailored to user needs to ensure smooth workflow implementation

Platform Compatibility

• File formats supported: JPG, TIF, OME.TIFF, ND2 (Nikon), MRXS (3DHistech), QPTIFF and component TIFF (Akoya), VSI (Olympus/Evident), NDPI and NDPIS (Hamamatsu), SVS and AFI (Aperio), CZI (Zeiss), SCN and LIF (Leica), BIF (Ventana), iSyntax and i2Syntax (Philips), KFB and KFBF (KFBIO), and DICOM whole-slide images
• Devices: Windows PC, Macintosh, and most tablets
• Browsers: Chrome (recommended) and Edge

Every HALO Link license includes unlimited IT support, scientific support, training, and access to the Indica Labs Learning Portal at no additional cost. With support staff located in the US, UK, EU, China, and Japan, users are covered across all time zones. HALO Link is also available as a cloud deployment through Indica Labs Cloud Services, offering a secure, scalable, and flexible alternative to on-premises installation.