Genedata Selector

Genedata Selector® is the only end-to-end enterprise software platform purpose-built to enable and accelerate next-generation sequencing (NGS)-based data analysis in GMP environments. Designed for biopharma, biotech, agricultural science, and industrial biotechnology teams, it serves as a single source of truth — empowering scientists to integrate, analyze, and share all project-related data without writing a single line of code. By automating NGS workflows, Genedata Selector can shorten assay turnaround by up to 90%, enabling faster, data-informed decisions across R&D and regulated development programs.

The platform is technology-agnostic, supporting sequencing systems from Illumina, PacBio, Oxford Nanopore Technologies, and others, allowing organizations to adopt new platforms without disrupting validated workflows. Genedata Selector is available for deployment both on-premises and in the cloud, adapting to existing infrastructure while maintaining full GxP compliance, traceability, and auditability.

Key Applications

• Biosafety Testing: Accelerates safe biotherapeutic development through early detection of harmful mutations and adventitious agents in raw materials, bulk harvests, and final products. Generates 21 CFR Part 11-compliant reports for regulatory submission.
• Cell Line Development: Streamlines NGS data analysis to confirm clone identity, refine host cell lines, and verify product integrity, stability, and purity. Supports CRISPR-driven engineering, single-cell RNA-seq for heterogeneity assessment, and comprehensive genome annotation including proprietary genomes, metabolic and signaling pathways, splice variants, microRNAs, mutations, and CNVs.
• Bioprocess Development: Monitors cellular pathways to identify engineering targets and bottlenecks, and detects cell variants via DNA-seq, RNA-seq, or mutation profiling to ensure product sequence integrity throughout development.
• Cell and Gene Therapy (CGT) Development: Automates and standardizes NGS data analysis to support Critical Quality Attribute (CQA) assessment, confirming identity, biosafety, and potency for regulatory compliance and consistent product quality.
• Industrial Biotechnology: Supports whole genome sequencing (WGS), cross-omics, and metagenomics to identify lead or indicator strains, streamline production strain development, and optimize processes for improved yield and performance.
• Agricultural Science: Enables whole-genome comparisons — from mutations to gene functions and pathways — to identify breeding and crop protection targets, bringing breeding and phytopathology teams together on a single collaborative platform.

Platform Modules

• Explorer: Centralizes public and proprietary genome data, including genotype–phenotype relationships, with intuitive visualizations of genome sequences, key genes, and variants at nucleotide and protein levels. Supports team collaboration through built-in notifications and shared views.
• Processor: Delivers a robust suite of bioinformatics tools with API-based integration of newly released tools. Automates standardized processing of raw NGS data across any sequencing technology, with built-in quality control, workflow validation, and interactive result visualization to ensure reproducibility.
• Analyst: Empowers researchers and biostatisticians to perform secure, scalable statistical analysis of complex datasets. Supports integration from common file formats and offers interactive visualization, data mapping, and built-in statistical applications including t-tests, ANOVA, linear models, machine learning, PCA, and PLS.
• Tracker: Manages sample metadata across the analysis pipeline with configurable, user-friendly interfaces for guided data entry. Enables filtering, searching, and visualization of sample information through dynamic graphs and lists, with GMP functionalities for complete sample history tracking and 21 CFR Part 11-compliant audit reports.
• Playbooks: Customizable, pre-configured guides powered by NextFlow pipelines that automate the entire NGS data analysis workflow — from sample registration and data processing to GMP-compliant reporting — covering a broad range of NGS-based assays across both R&D and cGMP environments.

Core Benefits and Capabilities

• Reduces assay time by up to 90% for product characterization and safety assessment workflows
• Automates and standardizes NGS data analysis workflows, reducing manual errors and increasing throughput
• Accelerates insight-driven decision-making through rapid results sharing and project documentation
• Ensures GxP-compliant data handling with full traceability from sample registration to report generation
• Simplifies and fully automates regulatory reporting in a validated environment
• Centralizes NGS data in a secure, structured environment supporting FAIR principles (findable, accessible, interoperable, reusable)
• Integrates seamlessly with lab instruments, LIMS, and enterprise systems across diverse sequencing platforms
• Delivers strong ROI by reducing cost per sample and making in-house NGS economical for both small- and large-scale projects

Genedata Selector integrates with lab instruments, LIMS, and broader enterprise systems, and supports NextFlow pipelines for scalable automation. Its secure, in-house analysis capabilities reduce the risk of exposing sensitive proprietary sequences to external parties, supporting both GxP and FAIR data compliance requirements across regulated and research environments.