FORECASTER

FORECASTER is an advanced computer-aided drug design (CADD) software platform developed by Molecular Forecaster Inc. (MFI). It is designed for preclinical drug design teams in both industry and academia, combining chemistry-driven predictive tools with biophysics and machine learning to accelerate the drug discovery process. The platform enables tailored experimental design and workflow automation entirely within its own ecosystem, without reliance on third-party applications.

FORECASTER provides continuous access to the latest advancements in CADD, supporting research programs at every stage. It is available under flexible licensing arrangements for both commercial organizations and academic institutions, making it accessible to a wide range of scientific teams.

Core Software Modules

• FITTED (Structure-based Drug Design): A docking tool with deep expertise in covalent drug design, including binding to metalloenzymes and other niche targets such as RNA. FITTED supports a broad range of structure-based drug design challenges with proven preclinical applicability.
• REACT2D (Virtual Library Design and Chemoinformatics): Employs advanced techniques in chemical searching, analoging, and clustering, alongside rigorous combinatorial chemistry workflows and chemistry fidelity checks to support virtual library design and exploration.
• IMPACTS (Metabolic Liabilities): Specializes in predicting Cytochrome P450 (CYP) enzyme activities, with a focus on CYP oxidation, inhibition, and induction, helping teams identify and address metabolic liabilities early in the drug design process.

Licensing and Access

• No usage limits: Site-based licenses allow unlimited users at every location, removing barriers to team-wide adoption.
• Simplified administration: No token-based systems — one straightforward price covers the software you need.
• Flexible installation: Available as local or cloud installations, with technical support included.
• Industry licensing: One or multi-year licenses sold at a set package price, with patch maintenance and support included.
• Academic licensing: Free licenses available to academic institutions with a professor or lab director signature, supporting the next generation of scientists.

Support and Integration

• MFI actively assists licensees throughout the duration of their license term to ensure successful integration of the software across all team members.
• Support is provided in the form of dedicated workshops and technical assistance hours.
• A comprehensive Resources page offers FAQs, parameters, software requirements, interim patch updates, online tutorials, and manuals.
• Users are encouraged to appropriately cite MFI publications when reporting results generated using FORECASTER tools.

FORECASTER is suitable for deployment in both local and cloud environments, and MFI's commitment to hands-on support ensures that teams can apply the platform's capabilities to their research projects efficiently from day one.