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FCS Express

Flow cytometry data analysis and visualization—from raw data to presentation-ready results with GLP and 21 CFR Part 11 compliance.

Solution by Dotmatics
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Overview

FCS Express by Dotmatics is a flow cytometry software solution designed to take researchers from raw data to presentation-ready results more quickly and easily than any other solution on the market. Built to serve a wide range of laboratory environments — from academic and research labs to clinical and regulated settings — FCS Express enables scientists to focus on their science rather than learning complex software tools.

Developed by De Novo Software, a Dotmatics company, FCS Express supports all types of cytometry workflows and is trusted by clinical laboratory professionals, pathologists, and researchers worldwide. It is notably the first third-party flow cytometry data analysis software listed with the FDA, making it a uniquely credible choice for regulated and clinical environments.

Core Capabilities and Features

  • Advanced Graphing: Create and format bar charts, pie charts, regression analyses, and trend lines, along with various formula functions, to facilitate visualization of relationships between statistics and how they combine to form a conceptual whole.
  • Integrated Spreadsheets: Link Excel-like spreadsheets directly to flow cytometry gates and data files, enabling users to work with live data. As gates move and data changes, spreadsheets update in real time, keeping all sources synchronized.
  • Publication-Ready Results: Generate high-quality graphics and reports directly within the software, eliminating the need to use multiple tools to present or publish results.
  • Ease of Use: The software is designed to look, feel, and work like familiar Microsoft Office programs, significantly reducing the learning curve so users can immediately focus on driving results rather than mastering new software.
  • Quality for Regulated Environments: FCS Express includes unique features specifically designed to help labs meet 21 CFR Part 11 compliance, supporting Good Laboratory Practice (GLP) and ensuring the quality and integrity of the analysis workflow in regulated environments.
  • FDA-Listed Clinical Edition: The FCS Express Clinical Edition is the first third-party flow cytometry data analysis software listed with the FDA, allowing clinical labs to confidently rely on the results generated by their instruments and software.

Analysis Tools for the Clinical Setting

  • FCS Express Clinical Edition provides specialized tools developed in collaboration with clinical laboratories, technicians, and pathologists around the world.
  • These tools are designed to address the unique challenges of performing data analysis in a clinical setting and to meet the specific requirements of clinical laboratory professionals.
  • De Novo Software is listed as a medical device manufacturer with the FDA, reinforcing the credibility and reliability of the Clinical Edition for regulated clinical use.

Workflow and Usability Benefits

  • Researchers can move from raw cytometry data to clearly communicated answers quickly and confidently.
  • The familiar interface design minimizes onboarding time, allowing users to become proficient before they even begin working with their data.
  • Real-time data linkage between gates, data files, and spreadsheets ensures that analysis remains consistent and up to date throughout the workflow.
  • The software supports all types of research labs, from academic through clinical and validated environments, making it a versatile solution across the life sciences.

FCS Express integrates with the broader Dotmatics platform ecosystem, including FCS Express Luma, which connects FCS Express outputs to the centralized Luma platform for streamlined flow cytometry data capture and traceability. This makes it well-suited for organizations seeking to unify their scientific data management alongside their cytometry analysis workflows.

Meta

Domain
Scientific Informatics & Analytical Platforms
Subdomain
Assay & Screening Data Management
Software type(s)
Analytical Platform
Deployment type(s)
Hybrid
Industry vertical(s)
Academic / ResearchBiotechCRODiagnostics / IVDPharma
Development stage(s)
ClinicalPreclinical / Pre-MarketResearch & Discovery
Target user(s)
Bench Scientist / Lab TechnicianLab Manager / Core Facility ManagerResearch ScientistClinical / Diagnostic Professional
Compliance standard(s)
21 CFR Part 11GxP