eCOA Platform

Clario's eCOA Platform is an electronic clinical outcome assessment solution designed for clinical trials of all sizes, including decentralized and hybrid studies. The platform supports patient-reported outcomes (PROs) and other endpoint data collection across the full trial lifecycle, drawing on 25 years of experience in DCT and hybrid trials across more than 120 countries and 100 languages.

The platform is built around flexible device options, pre-validated assessment libraries, and scientific expertise, with the goal of supporting enrollment, data quality, and regulatory compliance from study setup through completion.

Core Platform Capabilities

• Simplified design specification review to accelerate study build
• Greater configuration options to adapt to individual trial requirements
• Faster translations to support global deployment
• Pre-built, validated standardized assessment libraries
• Flexible technology options: bring-your-own-device (BYOD), web-based, or provisioned device
• Configurable platform that adapts to specific trial needs

eCOA Live

• Supports remote participation to increase enrollment flexibility for patients
• Enables electronic home assessments to minimize clinician bias and improve data reliability
• Delivers high-quality data more quickly to accelerate clinical trial timelines

eCOA Multimedia

• Enhances ePRO data with photos and audio recordings for richer insights
• Allows patients to track progress and monitor health using a single secure device
• Produces standardized, high-quality data to support more accurate results

Additional Solutions

• eCOA Neuroscience: Supports reliable, scalable, and regulatory-ready eCOA for global Central Nervous System (CNS) trials
• eCOA Rapid Start: Accelerates trial setup using pre-validated and configured eCOA assessments
• eCOA Science Services: Expert guidance for capturing regulatory-compliant data from the right participants, in clinic or at home
• eCOA Rescue Studies: Support for getting clinical trials back on track
• Rater Training and Participant and Caregiver Training: Training solutions to improve data accuracy and reduce scoring variability
• Suicidal Ideation Monitoring: Remote monitoring for suicidal ideation and behavior using the self-reported eC-SSRS combined with a telehealth video visit service

Accessibility Features

• Zoom In/Zoom Out: Increases accessibility for participants with visual impairments, reduces reliance on caregiver assistance, eliminates the need for external reading aids, and ensures all answer options remain visible through science-led design validated for equivalency
• Dark Mode: Offers a choice between dark and light mode, reduces light sensitivity for participants prone to conditions such as migraines, provides higher contrast between text and background, and reduces eye strain in low-light conditions

Connected Devices

• Devices are pre-validated for clinical trial use and integrated with the eCOA device
• Supported connected devices include: Alivecor KardiaMobile6L (ECG), Go Spiro (spirometry), Glucometer (blood glucose), Opal Precision Motion Monitoring (movement endpoints), Ametris Watch (activity levels), and Ultrasonic Sensor

Device Modalities

• Provisioned devices
• Tablets
• Bring-your-own-device (BYOD) via smartphone or tablet
• Home computer (web-based access)

Scientific and Therapeutic Area Expertise

• Scientific and therapeutic area experts are available to advise on appropriate eCOA endpoints and assessments early in clinical development programs
• Tailored solutions have been developed across more than 560 indications
• Therapeutic areas covered include: Neuroscience, Oncology, Endocrinology, Respiratory, Dermatology, Immunology, Vaccines, Gastroenterology, Musculoskeletal, Cardiovascular and Metabolic, and Women's Health

Clario's eCOA Platform supports global deployment across decentralized, hybrid, and site-based trial models. A paper-cost calculator is available to help sponsors estimate the potential expense of paper-based PRO collection before initiating a trial.