CLC Genomics Server

QIAGEN CLC Genomics Server is an advanced, high-throughput sequencing-focused bioinformatics computing platform designed for organizations that need a centralized, secure, and scalable solution for next-generation sequencing (NGS) data analysis. Built on a three-tier system architecture, it provides powerful and flexible bioinformatics services across genomics, transcriptomics, and epigenomics, making it suitable for research teams and bioinformatics groups handling large volumes of sequencing data. The platform is intended for molecular biology applications and is not intended for the diagnosis, prevention, or treatment of disease.

CLC Genomics Server is available in two subscription tiers: the Master Plus edition, which provides a static license with maintenance, upgrades, and service; and the Premium edition, which additionally includes extensions for CLC Microbial Genomics, CLC LightSpeed Module, CLC Single Cell Analysis, and CLC Genome Finishing Server.

Key Features

• Central execution platform with a flexible queuing system for managing bioinformatics jobs
• Maximum client flexibility with full support for CLC Genomics Workbench as a premium client
• Highly customizable on both client- and server-side to meet diverse organizational needs
• Advanced and customizable data import/export framework
• Central data storage for managing and securing large genomics datasets

Performance and Scalability

• Offers three client options: CLC Genomics Workbench, CLC Server Command Line Tools, and a web interface — all built on service-oriented SOAP web services
• Supports custom client development, giving teams complete flexibility on the client side
• All client-to-server connections are secured through SSL
• Designed for advanced customization through plugin development and integration of external applications
• Built-in Job Node support allows attachment of real or virtualized computers as execution points, enabling scalable bioinformatics computing
• Server jobs can be distributed from a master server to grid nodes, with support for third-party grid scheduling systems including OGE, PBS Pro, and IBM Platform LSF (tested versions: OGE 6.2u6, PBS Pro 11.0, LSF 8.3 and 9.1)

Data Management

• Flexible data management architecture designed to handle large amounts of genomics data
• Built-in tools for restricting access and managing bioinformatics data across teams and projects
• Supports secure, centralized storage within the organization's own infrastructure

Applications

• Supports a broad range of bioinformatics analysis services on high-throughput sequencing data
• CLC Genomics Workbench client supports key NGS features including read mapping within genomics, transcriptomics, and epigenomics workflows
• Applicable across research areas requiring large-scale sequencing data processing and analysis

CLC Genomics Server is deployed as a server-architecture solution located centrally within an organization, providing a stable software core that integrates with QIAGEN's broader CLC bioinformatics ecosystem. Subscriptions include maintenance, upgrades, and service support.