ActiveLIMS

ActiveLIMS is a Laboratory Information Management System (LIMS) developed by ATGC Labs, designed to annotate, collect, manage, and provide access to research biology data generated during drug screening and discovery. Built around a flexible, robust architecture, it is purpose-built for life science laboratories that need to handle data from diverse assay technology platforms operating in high-throughput mode. ActiveLIMS is suited for pharmaceutical companies, academic research institutions, hospitals, and contract research organizations seeking to replace error-prone spreadsheet-based workflows with a centralized, scalable data management solution.

ActiveLIMS addresses the common challenges laboratories face as spreadsheets grow unwieldy — including version control issues, difficulty synchronizing data across platforms, and inconsistent data views. By providing a centralized data store for compound and assay data, along with integrated tools for analysis and reporting, ActiveLIMS enables laboratories to move toward fully paperless operations and significantly improve productivity.

Core Capabilities

• Fully customizable, multi-level, flexible component-based system capable of managing any type of sample and associated data
• Freedom to create any laboratory workflow in minutes, with a highly customizable interface that can meet diverse customer requirements
• Instrument-independent architecture, allowing laboratories to choose their own instruments with confidence that integration will be supported
• Instrument integration and control for liquid handling and assay result measurement, including support for SpectraMax, TaqMan, Biomek, and Protedyne platforms
• Custom integration capabilities with any third-party systems present in the laboratory
• Paperless solutions achieved through interfacing with lab equipment and incorporating statistical packages

Major Modules

• Animal Studies and Facilities: Prepare, submit, and track animal studies end-to-end
• Assay Management (ELISA, qPCR): Facilitates best-practice business processes for analytical data requests, quality control, and quality assurance
• Liquid Transfer and Instrument Data Management: Supports liquid handling platforms (Biomek, Protedyne) and instrument data management (SpectraMax, TaqMan) to properly log, manage, analyze, visualize, and report large volumes of raw data
• Freezer Inventory: Fully customizable freezer configuration compatible with all freezer types, tank racking systems, and cryo storage units
• Samples Module: Manages all sample data with an unlimited number of custom-defined fields
• Experiments Module: Supports chemists, physicists, biologists, and other scientists in conducting a wide variety of tests and experiments
• Document and Record Management: Provides document management, web content management, and record management functionality using an open standard API to communicate with diverse document management systems and repositories
• RESTful Web Services API: Supports bi-directional integration with external systems via a RESTful Web Services API

Technical Architecture and Database Support

• Works with industry-standard database platforms including Microsoft SQL Server, Oracle, MySQL, and PostgreSQL, delivering a true operating system and database independent solution
• Web-based client/server architecture enabling secure data access from anywhere, at any time
• Agile system design intended to increase overall laboratory productivity

ActiveLIMS meets GLP and FDA guidelines, including 21 CFR Part 11 requirements, making it suitable for regulated laboratory environments. The platform is trusted by a broad range of customers globally, including leading pharmaceutical companies such as GlaxoSmithKline and Alnylam Pharmaceuticals, major research universities including Johns Hopkins, Duke, and the University of Toronto, as well as hospitals, forensic science centers, and biotechnology firms.