Rune Labs

Rune Labs is a software and data analytics company focused on precision neurology, supporting both clinical care delivery and therapy development. Founded in San Francisco in 2018, Rune Labs builds tools that connect neurophysiology data, real-world evidence, and advanced analytics to improve outcomes for patients with neurological disorders — with a primary focus on Parkinson's disease and an expanding presence in Multiple Sclerosis, OCD, and Essential Tremor.

Rune Labs serves two core audiences: clinicians and patients who need better tools for managing complex neurological conditions, and life sciences companies seeking to accelerate therapy development using real-world data. The company has received FDA 510(k) clearance for its StrivePD ecosystem on Apple Watch for Parkinson's symptom monitoring, and has demonstrated meaningful clinical impact — including nearly halving emergency room visits for Parkinson's patients in a program with Kaiser Permanente.

StrivePD: Care Delivery Ecosystem for Parkinson's Disease

• Personalized symptom summaries and data-enriched care workflows designed to give clinicians a curated view of each patient's condition
• Custom workflows built for select advanced therapies, enabling more tailored clinical decision-making
• Patient influence over care decisions through direct engagement with their own health data
• Symptom and medication tracking via Apple Watch and a dedicated patient app
• FDA-cleared for Parkinson's disease monitoring through the StrivePD ecosystem on Apple Watch, with clearance secured in June 2022
• Includes a Parkinson's AI Companion trained on the world's largest Parkinson's dataset, launched in 2024

Solutions for Life Sciences

• Clinical trial support encompassing data collection, enriched trial recruitment, and synthetic control cohorts to streamline development programs
• Real-world evidence generation leveraging patients, data, and technology from the StrivePD platform
• Commercial channels and therapy adoption facilitated through tailored clinician workflows
• Pioneered the use of real-world data in neurodegenerative diseases, providing access to a network of engaged clinicians and patients alongside large longitudinal datasets
• Launched StriveStudy in March 2023, a clinical trial platform designed to accelerate the development of precision neurology therapies
• Collaborating with BlueRock Therapeutics to better characterize Parkinson's disease state in cell therapy trials

Expanding Neurology Capabilities

• Identifying quantitative biomarkers of MS lesions through ongoing research initiatives
• Conducting research in OCD to capture symptoms and wearable data via Rune Labs technology
• Extending precision neurology expertise to Essential Tremor and other neurodegenerative conditions
• Academic and research facility partnerships support the company's broader scientific mission
• Published research featured in Frontiers in Human Neuroscience and iScience, including work on digital chronotherapy and bioelectronic medicines

Company Milestones and Funding

• Founded in October 2018 in San Francisco
• Closed a $5M Seed Financing round in October 2020, led by DigiTx Partners
• Closed a $22.8M Series A round in September 2021, led by Eclipse Ventures
• Secured a $12M strategic round in January 2024 to accelerate adoption of novel Parkinson's disease technologies
• Board of Directors includes representatives from Eclipse Ventures, DigiTx Partners, and Kaia Health

Culture and Values

• Patient-centered design is foundational — all employees share a mission to improve patient lives and advance better treatments for brain disease
• Diversity and inclusion are treated as necessities, with active investment in ensuring no group is excluded or underrepresented
• Transparency and connectivity are prioritized across a distributed, cross-functional team through all-hands meetings, team on-sites, and open communication channels
• Ethical standards and data privacy are upheld rigorously — legal agreements are purposefully designed to prevent misuse of patient data, and patient risk is evaluated at every phase of engineering
• Employee wellbeing is supported through flexible vacation policies, adaptable work arrangements, and a culture that encourages individuals to bring their whole selves to work

Rune Labs combines a deeply human-centered philosophy with rigorous scientific and engineering capabilities, positioning itself as a long-term partner for clinicians, patients, and life sciences organizations working to transform the future of neurological care.