Pulse Infoframe

Pulse Infoframe is a global healthcare technology company that has developed a real-world evidence platform supporting clinical research in oncology, rare disease, and other complex conditions for more than a decade. The company collaborates with biopharmaceutical companies, research institutions, and patient advocacy groups to enable the collection and sharing of high-quality data for research, regulatory submissions, and advancements in personalized medicine.

The company's cloud-based platform supports the integration and analysis of diverse data sets, including harmonization of novel data collected directly from sites and patients with existing data from registries and clinical trials. Pulse Infoframe has supported longitudinal prospective studies and registries across more than 25 diseases — including melanoma, lung cancer, and CDKL5 — in partnership with more than 10 global pharmaceutical partners seeking to understand natural history of disease, treatment effectiveness, and burden of illness.

Core Platform: healthie™

• The healthie™ platform is Pulse Infoframe's evidence generation platform designed to engage patients, caregivers, study coordinators, advocates, and industry stakeholders.
• Includes consent management tools, an educational materials library, a repository of patient-reported outcome measures, and natural and disease-specific data elements that can be readily deployed.
• Data collected through the platform is mapped to Observational Medical Outcomes Partnership (OMOP), mCode, and other standards.
• Supports consented data-sharing permissioning across stakeholders and meets regulatory standards required by the FDA and EMA.
• The platform adjusts to support communities worldwide, with compliant consenting and governance procedures enabling researchers globally to access shared data.

Key Capabilities

• Acceleration of clinical research start-up timelines and centralization of real-world data.
• Integration and harmonization of data from multiple sources, including sites, registries, and clinical trials.
• Support for longitudinal prospective studies and disease registries across oncology, rare disease, and chronic conditions.
• Generation of insights to support drug development, regulatory submissions, and understanding of rare and complex diseases.
• A Pulse Discovery offering described as de-risking clinical research.
• A Rare Central product listed alongside healthie™ as part of the company's solution portfolio.

Team and Scientific Foundation

• The in-house research and epidemiology team does not outsource its science, and their expertise forms the foundation of platform development.
• Team members bring experience from organizations including ConcertAI, Oracle (Cancer Research Cloud), PatientsLikeMe, CureForward, Salesforce, N-of-One, Apple, Optum, and Brigham & Women's Hospital.
• The team collectively holds more than 200 peer-reviewed publications.
• Pulse Infoframe maintains a Scientific Advisory Board and a global Principal Investigator network.

Partnerships and Compliance

• Works with leading biopharmaceutical companies, key opinion leaders, research institutions, and patient advocacy groups.
• Develops trusted relationships with data partners to expand data collection across sites, stakeholders, and data sources.
• Platform is globally compliant, meeting FDA and EMA regulatory standards for data sharing and governance.
• Disease areas of focus include cancer (e.g., uveal melanoma, lung cancer), rare diseases (e.g., GM2 Gangliosidosis, CDKL5), and chronic conditions.

Pulse Infoframe positions itself as a science-driven, collaboration-focused platform company, with its work described as bridging the gap between data and decision-making in healthcare globally.