PPD

PPD focuses on harnessing real-world evidence (RWE) to enhance product safety, effectiveness, and market access. The increasing acceptance of RWE by regulators and health technology assessment bodies, along with the demand from patients and healthcare providers for transparency, is transforming how RWE is generated and utilized.

RWE is integrated at every stage of the product lifecycle, from early discovery to post-market, complementing clinical trial data by offering real-world context and broader patient representation. This approach allows for a more accurate assessment of comparative effectiveness, safety outcomes, and long-term benefits.

PPD aligns clinical and real-world needs by providing solutions that identify the right evidence for the right audience at the right time. By leveraging real-world data (RWD), they unlock insights that inform decision-making, improve patient outcomes, and drive innovation.

Real-world evidence to inform decision-making

RWE provides value from early development stages, even before clinical trials begin, and continues beyond market access. It benefits the development path by:

• Informing clinical trial design, improving patient recruitment, and optimizing endpoints for efficient trials
• Assessing comparative effectiveness, safety outcomes, and long-term benefits
• Enabling proactive monitoring and risk management for patient safety
• Informing post-approval commitments and regulatory assessments
• Supporting value-based pricing and reimbursement decisions
• Facilitating shared decision-making and personalized care
• Identifying barriers to patient uptake and mitigating challenges

PPD's multidisciplinary global team of experts provides fit-for-purpose solutions to address challenging research questions across the development lifecycle.

Observational studies

Observational studies are crucial for generating data to answer specific research questions, ensuring study designs meet needs related to feasibility, clinical trial design, safety, or product effectiveness.

Comprehensive, proprietary longitudinal data

PPD's proprietary CorEvitas Registries capture robust, regulatory-grade clinician- and patient-reported data, providing invaluable information on treatment patterns and outcomes.

Data and scientific solutions

With the exponential growth of real-world data sources, PPD applies data science and analysis to generate impactful evidence and advance products.

Pregnancy and lactation studies

PPD generates comprehensive evidence to support product use in pregnant and lactating individuals, addressing historically insufficient data in these subpopulations.

Patient-centered research

PPD prioritizes patient engagement throughout drug development, integrating patient perspectives into trial and study designs to improve outcomes.

Implementation science

PPD uses innovative research approaches to address barriers to product uptake, optimizing real-world product usage and success.

With nearly 40 years of experience, PPD's Evidera Real-World Evidence team provides strategic and scientific guidance, enabling clients to deliver life-changing interventions.