Pluto Biosciences

Pluto Bio is a multi-omics platform purpose-built for translational discovery in drug development and life sciences research. The platform serves as a unified workspace that takes teams from flexible data exploration through to structured translational decisions, removing ambiguity and increasing confidence with review-ready evidence. Pluto Bio is designed for interdisciplinary scientific teams across pharmaceutical and biotech companies, academic research institutions, and contract research organizations (CROs).

At its core, Pluto Bio combines data management, bioinformatics analysis, and visualization into a single secure, cloud-based environment. The platform emphasizes end-to-end traceability, no-code accessibility, and real-time collaboration, enabling biology teams to translate raw multi-omics data into actionable biological insight faster than traditional workflows allow.

Translational Decision Platform

• Provides a unified home for preclinical and translational strategy, enabling multi-site, interdisciplinary collaboration in real time
• Allows teams to design and communicate program strategy, track key results, and organize data and knowledge sources around a common scientific mission
• Features a no-code canvas for exploring data and testing scientific hypotheses, bringing results to life while maintaining full traceability
• Supports target identification, target status tracking, biomarker discovery, and mechanism elucidation
• Organizes and makes searchable all experiments, plots, data, and files within a secure cloud environment

Supported Assays and Bioinformatics Capabilities

• Featured end-to-end single-cell RNA-seq (scRNA-seq) workflow designed with biologists in mind, covering raw data ingestion, preprocessing customization, cell type annotation, and flexible downstream analysis
• Supports a broad range of additional assays including bulk RNA-seq, ChIP-seq, CUT&RUN, ATAC-seq, PRO-seq, Spatial Transcriptomics, proteomics, and metabolomics
• Pipelines available for plate-based and custom assays
• Ability to import GEO studies from FASTQ files through full analysis, streamlining NGS workflows with minimal hands-on time
• Supports batch effect correction and harmonization across multi-omics datasets
• Enables cell summary analysis to support translational teams in interpreting complex single-cell data
• Supports genomic data visualization including bigWig file handling integrated into broader workflows

Core Platform Capabilities

• No-code data visualization and interactive figure generation for publication-quality results
• Results management with end-to-end traceability across experiments and analyses
• Centralized multi-omics data management in a secure cloud environment
• Real-time collaboration across teams, sites, and institutions
• Scalable foundation designed specifically for biology and scientific teams
• Integration with public datasets such as the Cancer Cell Line Encyclopedia (CCLE) to accelerate cancer research, biomarker discovery, and therapy testing

Solutions by Audience

• Pharma and Translational Science teams use Pluto Bio to hit program milestones faster, translating raw data into insight across target identification, biomarker discovery, and comparative translational studies
• Academic research labs leverage the platform to generate publication-ready figures quickly, increase reproducibility and data accessibility, and collaborate seamlessly across institutes
• CROs and consultants use Pluto Bio to manage multiple clients and projects at scale through a streamlined web application, delivering bespoke, interactive, and traceable results to their own clients without the burden of maintaining custom software infrastructure

Company and Deployment Details

• Delivered as a secure, cloud-based web application accessible without specialized infrastructure setup
• Raised $3.6 million in funding to expand its AI-powered multi-omics analysis platform for pharma, with investment led by Kickstart and continued support from Silverton Partners
• Actively publishing a learning series covering topics such as translational bioinformatics, batch effect correction, single-cell data challenges, and integrated multi-omics workflows

Pluto Bio is positioned as a modern productivity platform specific to science, helping discovery and translational teams eliminate fragmented data workflows, reduce bottlenecks in bioinformatics analysis, and accelerate the path from biological data to confident, evidence-backed decisions.