Metrum Research Group

Metrum Research Group (MetrumRG), established in 2004, is a quantitative sciences consulting and technology firm focused on biomedical modeling and simulation for drug development. The company serves pharmaceutical, biotechnology, and other life sciences organizations, having supported data-driven decision making for over 200 companies across more than 900 projects. MetrumRG operates at the intersection of data, science, and technology, providing scientific expertise to help clients advance drug development programs and address unmet medical needs.

The company's work is organized around two primary areas: consulting and project services delivered by a team of modeling and simulation scientists, and technology solutions centered on its Metworx cloud computing platform. MetrumRG also maintains a commitment to open science, sharing tools, methods, and educational content freely with the broader scientific community.

Core Services

• Strategic consulting and full project support for drug development programs, with each project customized to client needs and staffed by collaborative teams of modeling and simulation scientists.
• Data-driven decision making support across all stages of drug development.
• Quantitative Systems Pharmacology (QSP) modeling, led by a dedicated vice president and specialist team.
• Pharmacokinetics and pharmacodynamics (PKPD) modeling and analysis, with multiple group leaders and senior scientists in this discipline.
• Statistical bioinformatics and applied data science services.
• Strategic advisory solutions provided through principal consultants with deep industry experience.

Technology Solutions — Metworx

• Metworx is MetrumRG's cloud computing platform designed for quantitative scientists working in drug development.
• The platform provides access to commonly used modeling and simulation tools through a cloud-based environment, enabling scientists to gain efficiencies without managing underlying infrastructure.
• Metworx is supported by a dedicated technology solutions team that includes software engineers, site reliability engineers, DevOps engineers, solutions engineers, and product management professionals.
• The technology solutions division has its own president, vice president of engineering, director of software engineering, and director of product management, indicating a substantial standalone organizational structure.

Open Science Initiatives

• MetrumRG is committed to openly sharing principles, methods, and tools with the scientific community as part of its organizational philosophy.
• The company offers free educational courses aimed at scientists and future scientists who wish to apply quantitative approaches to drug development.
• A number of open source tools are made available to the broader community, reflecting the company's belief that knowledge and methods should be shared openly as they are developed.

Team and Organizational Structure

• MetrumRG employs a multidisciplinary team spanning pharmacology, pharmacokinetics, statistics, bioinformatics, data science, software engineering, and systems biology.
• Scientific staff hold advanced degrees including Ph.D. and Pharm.D. qualifications across a range of relevant disciplines.
• The organization includes dedicated functions for quality, project management, resource management, business development, and science communications.
• Leadership includes a Chief Executive Officer, President of Quantitative Sciences, President of Technology Solutions, and Vice Presidents across PKPD, QSP, and Engineering.
• The company designates senior fellows and principal scientists, reflecting a structured scientific career track alongside its technology and business functions.

MetrumRG positions itself as both a scientific services provider and a technology company, combining project-based consulting with a proprietary cloud platform and a publicly stated commitment to open science and community knowledge sharing.