Igenbio

Igenbio, Inc. is a Chicago-based company that develops genomics and bioinformatics analysis products and services for the life sciences industry. Founded in 1997, the company has a track record spanning two decades of delivering scientific results for academic, governmental, and industrial institutions. Igenbio's scientists hold broad experience in both in silico and wet lab sequencing and research and development, with more than 100 relevant publications in these areas.

Igenbio serves a wide range of customers including Fortune 500 companies, universities, and government research centers. Notable organizations that have worked with Igenbio include Procter & Gamble, Cargill, Evonik, DANONE, NEB (New England Biolabs), KRIBB, and TMO Renewables, among others.

ERGO 2.0 Informatics Platform

• ERGO 2.0 is Igenbio's cloud-based integrated genomics and bioinformatics platform, designed to help industrial, academic, and medical scientists develop knowledge from existing and new DNA sequencing projects.
• The platform contains a curated database integrated with synthetic biology tools to support faster product creation.
• Key features include a Whole Genome Annotation Platform, Metagenome and Microbiome Analysis, Differential Gene Expression Analysis, Variant Detection and Analysis, Genome Browser, and Metabolic Analysis.
• ERGO 2.0 includes ERGO Workflows, an Application Programmer Interface (API), and support for interactive visualizations and statistical analysis.
• Recent additions to the platform include Metabolomics Data Integration, MetaCyc/EcoCyc/BioCyc Pathway Database Integration, Feature Lists, Bulk Downloads, Functional Prediction for 16S Amplicon Sequencing data, PERMANOVA and additional ordination methods for microbiome analysis, and Violin Plots for Expression Analysis.
• A 14-day free trial is available for new users.
• ERGO™ and Integrated Genomics™ are registered trademarks of Igenbio, Inc.

Genomic Services

• Whole Genome Sequencing (WGS): High-quality sequencing services supporting Illumina, PacBio, Hi-C, and Oxford Nanopore technologies, with multiple coverage options (30x, 60x, and greater than 100x), fast turnaround, and CLIA-compliant options available.
• Microbiome Sequencing and Analysis: Expert sequencing and analysis of microbial communities from both cultivable and non-cultivable microbes, including RNA/DNA extraction from environmental and clinical samples, Amplicon sequencing (16S rRNA, ITS, and custom), whole metagenome shotgun sequencing, metatranscriptomics, and bioinformatics and statistical analysis.
• RNA Sequencing (RNA-Seq): End-to-end services covering experimental design, RNA extraction, high-quality sequencing (PacBio, Illumina, and Nanopore), bioinformatics analysis, and interactive visualizations and statistical analysis through ERGO. Services also cover microarray and other expression studies.
• Genome Assembly and Annotation: Assembly services for viral, prokaryotic, eukaryotic, haploid, diploid, and polyploid genomes using all current sequencing technologies including Illumina, PacBio, Oxford Nanopore, 10x, Hi-C, and Ion Torrent. Assembly strategies include de novo, reference-based, hybrid, and metagenomic approaches. Annotation services cover prokaryotic, fungal, animal, and plant organisms, with gene annotation and functional assignments using KEGG Pathways, Gene Ontology, and the ERGO database, as well as identification of antibiotic resistance genes, pathways, and specific drugs.
• Metabolic Reconstruction: Deduction of metabolic reconstructions using ERGO's analytical tools.
• Custom Analysis Pipelines: Development of tailored bioinformatics workflows to meet specific project requirements.
• Growth Media Design and Microbial Metabolic Engineering: Services supporting the design of growth media and the engineering of microbial metabolism.
• Variant Detection, Annotation, and Analysis: Identification and characterization of genomic variants.
• Regulatory Filing Support: Assistance with Generally Recognized as Safe (GRAS) and European Food Safety Authority (EFSA) regulatory filings.

Company Background and Credentials

• Igenbio's scientists have decades of combined experience in biology and computer science, with results published in peer-reviewed literature.
• The company's genome assembly and annotation methods have been featured in dozens of peer-reviewed publications and are used by institutions worldwide.
• Igenbio has served customers across multiple industries including consumer goods, food and agriculture, industrial biotechnology, biofuels, and academic and government research.
• The company is headquartered at 1016 W Jackson Blvd., Chicago, IL 60607, and can be reached by phone during standard business hours.

Igenbio offers both its ERGO 2.0 software platform and a full suite of expert genomic services, positioning itself as a combined informatics and laboratory services provider for organizations seeking to translate sequencing data into actionable biological knowledge.