GenBioAI

GenBio AI is an artificial intelligence research company pioneering the development of multiscale AI foundation models designed to decode and simulate human biology. The company's overarching mission is to build the world's first AI-Driven Digital Organism (AIDO) — an interactive, programmable virtual cell that makes biology computable, predictable, and ultimately programmable. By connecting biological information across scales, from molecules to phenotypes, GenBio AI aims to accelerate breakthroughs in medicine, biotechnology, and the broader life sciences.

Co-founded by Eric Xing (Chief Scientist) and David Baker, GenBio AI operates at the frontier of generative biology research, with the conviction that simulating biology with precision will transform disease treatment from a decades-long gamble into an engineering problem. The company's models and research outputs are made available to the scientific community via Hugging Face and GitHub.

Core Platform: AIDO (AI-Driven Digital Organism)

• AIDO is a world model for biology that integrates information across multiple biological scales, from molecular interactions to whole-organism phenotypes.
• The system enables prediction, generation, and simulation of biological processes, including modeling the behavior of a virtual cell.
• AIDO is described as a Digital Living System designed to provide actionable insights for healthcare, green technologies, and consumer innovation.
• The platform supports applications across drug discovery, disease understanding, and personalized medicine.

Foundation Models

• K2 — A 70B+ parameter model recognized as the most advanced foundation model in GenBio AI's portfolio, released in 2024.
• World's Largest Genome Foundation Model — A 15B+ parameter genome foundation model, the largest of its kind, released in 2024, with research demonstrating that accurate and general DNA representations emerge from genome foundation models at scale.
• World's Largest Protein Foundation Model — A 100B+ parameter protein foundation model, the largest in the world, released in 2024, leveraging Mixture of Experts architecture to enable efficient and effective protein understanding and design.
• World's Largest RNA Foundation Model — A 7B+ parameter RNA foundation model, released in 2024.
• Collectively, these models achieve state-of-the-art performance across more than 300 biological tasks.

Key Use Cases

• Drug Discovery: Accelerates drug development by simulating millions of potential treatments and predicting their effects on complex biological systems.
• Disease Understanding: Equips researchers with models to investigate the mechanisms underlying conditions such as cancer and neurodegenerative diseases.
• Personalized Medicine: Enables digital patient simulations to minimize adverse reactions and improve the effectiveness of treatments for individual patients.

Research Highlights

• Published research on the AIDO framework: Toward AI-Driven Digital Organism: A System of Multiscale Foundation Models for Predicting, Simulating and Programming Biology at All Levels.
• Research on genome-scale modeling: Accurate and General DNA Representations Emerge from Genome Foundation Models at Scale.
• Research on protein modeling: Mixture of Experts Enable Efficient and Effective Protein Understanding and Design.

GenBio AI's technology is positioned to serve researchers, healthcare organizations, and innovators across life sciences, offering a comprehensive suite of foundation models and a scalable biological simulation platform aimed at generating lasting scientific and societal impact.